Caplyta and Bi-polar - a phase IV clinical study of FDA data

Summary:

Bi-polar is reported as a side effect among people who take Caplyta (lumateperone tosylate), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Lamictal, and have Schizophrenia.

The phase IV clinical study analyzes which people have Bi-polar when taking Caplyta. It is created by eHealthMe based on reports of 3,083 people who have side effects when taking Caplyta from the FDA, and is updated regularly.

What is Caplyta?

Caplyta has active ingredients of lumateperone tosylate. eHealthMe is studying from 3,109 Caplyta users. Check the latest studies of Caplyta.

What is Bi-polar?

Bi-polar is found to be associated with 887 drugs and 1,211 conditions by eHealthMe. Check the latest studies of Bi-polar.

On Jul, 13, 2026

3,083 people reported to have side effects when taking Caplyta.
Among them, 11 people (0.36%) have Bi-polar.

Among these 11 people:

How long have people been on Caplyta when they have Bi-polar? *

What is the gender of people who have Bi-polar when taking Caplyta? *

female: 40 %
male: 60 %

What is the age of people who have Bi-polar when taking Caplyta? *

What are other drugs people take besides Caplyta? *

Lamictal: 2 people, 18.18%
Xywav: 1 person, 9.09%
Alcohol: 1 person, 9.09%
Amlodipine Besylate: 1 person, 9.09%
Austedo: 1 person, 9.09%
Fanapt: 1 person, 9.09%
Glipizide: 1 person, 9.09%
Hydroxyzine Hydrochloride: 1 person, 9.09%
Intuniv: 1 person, 9.09%
Jardiance: 1 person, 9.09%

What are other side effects people have besides Bi-polar? *

Stress And Anxiety: 2 people, 18.18%
Mania (a state of abnormally elevated or irritable mood): 2 people, 18.18%
Weight Increased: 1 person, 9.09%
Glucose Tolerance Impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis): 1 person, 9.09%
Borderline Personality Disorder: 1 person, 9.09%
Cardiac Arrest: 1 person, 9.09%
Delusion (a false belief or opinion): 1 person, 9.09%
Dizziness: 1 person, 9.09%
Drowsiness: 1 person, 9.09%
Drug Hypersensitivity: 1 person, 9.09%

What are the existing conditions these people have? *

Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 18.18%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 9.09%
Mania (a state of abnormally elevated or irritable mood): 1 person, 9.09%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 1 person, 9.09%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Caplyta and have Bi-polar?

- Check whether Bi-polar is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Caplyta:

Caplyta (3,109 reports)

Bi-polar treatments and more:

Bi-polar (109,428 reports)

Browse all side effects of Caplyta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bi-polar:

Bi-polar (887 drugs)

Browse all the conditions that are associated with Bi-polar:

Bi-polar (1,211 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lumateperone tosylate (the active ingredients of Caplyta) and Caplyta (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.