Carafate and Diastolic dysfunction - a phase IV clinical study of FDA data

Summary:

Diastolic dysfunction is reported as a side effect among people who take Carafate (sucralfate), especially for people who are female, 60+ old, also take Protonix, and have Metastases to bone.

The phase IV clinical study analyzes which people have Diastolic dysfunction when taking Carafate. It is created by eHealthMe based on reports of 13,583 people who have side effects when taking Carafate from the FDA, and is updated regularly.

What is Carafate?

Carafate has active ingredients of sucralfate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 14,029 Carafate users. Check the latest studies of Carafate.

What is Diastolic dysfunction?

Diastolic dysfunction is found to be associated with 677 drugs and 631 conditions by eHealthMe. Check the latest studies of Diastolic dysfunction.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

13,583 people reported to have side effects when taking Carafate.
Among them, 17 people (0.13%) have Diastolic dysfunction.

Could Carafate cause Diastolic dysfunction?

Among these 17 people:

What is the gender of people who have Diastolic dysfunction when taking Carafate? *

female: 64.71 %
male: 35.29 %

What is the age of people who have Diastolic dysfunction when taking Carafate? *

What are other drugs people take besides Carafate? *

What are other side effects people have besides Diastolic dysfunction? *

Tricuspid Valve Incompetence (inefficient heart valve): 13 people, 76.47%
Nausea (feeling of having an urge to vomit): 12 people, 70.59%
Dyspnea (difficult or laboured breathing): 12 people, 70.59%
Mitral Valve Incompetence (inefficient heart valve): 11 people, 64.71%
Dizziness: 11 people, 64.71%
Cough: 11 people, 64.71%
Chest Pain: 11 people, 64.71%
Joint Pain: 10 people, 58.82%
Stress And Anxiety: 9 people, 52.94%
Oedema Peripheral (superficial swelling): 9 people, 52.94%

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 4 people, 23.53%
Multiple Myeloma (cancer of the plasma cells): 3 people, 17.65%
Breast Cancer: 3 people, 17.65%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 11.76%
Bone Loss: 2 people, 11.76%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 1 person, 5.88%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 1 person, 5.88%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 5.88%
Breast Cancer Metastatic: 1 person, 5.88%
Hypomania (a mild form of mania, marked by elation and hyperactivity): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Carafate and have Diastolic dysfunction?

- Check whether Diastolic dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Carafate:

Carafate (14,029 reports)

Browse all side effects of Carafate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Diastolic dysfunction:

Diastolic dysfunction (677 drugs)

Browse all the conditions that are associated with Diastolic dysfunction:

Diastolic dysfunction (631 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sucralfate (the active ingredients of Carafate) and Carafate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.