Cardizem and Listless - a phase IV clinical study of FDA data

Summary:

Listless is reported as a side effect among people who take Cardizem (diltiazem hydrochloride), especially for people who are male, 60+ old, also take Axid, and have Blood iron decreased.

The phase IV clinical study analyzes which people have Listless when taking Cardizem. It is created by eHealthMe based on reports of 27,075 people who have side effects when taking Cardizem from the FDA, and is updated regularly.

What is Cardizem?

Cardizem has active ingredients of diltiazem hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 28,014 Cardizem users. Check the latest studies of Cardizem.

What is Listless?

Listless (lack of interest, energy, or spirit) is found to be associated with 456 drugs and 654 conditions by eHealthMe. Check the latest studies of Listless.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

27,075 people reported to have side effects when taking Cardizem.
Among them, 13 people (0.05%) have Listless.

Among these 13 people:

What is the gender of people who have Listless when taking Cardizem? *

female: 30.77 %
male: 69.23 %

What is the age of people who have Listless when taking Cardizem? *

What are other drugs people take besides Cardizem? *

What are other side effects people have besides Listless? *

Fatigue (feeling of tiredness): 11 people, 84.62%
Dizziness: 6 people, 46.15%
Weakness: 5 people, 38.46%
Chest Pain: 5 people, 38.46%
Hypotension (abnormally low blood pressure): 4 people, 30.77%
Pain: 4 people, 30.77%
Gamma-Glutamyltransferase Increased: 3 people, 23.08%
Mental Status Changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 3 people, 23.08%
Nausea (feeling of having an urge to vomit): 3 people, 23.08%
Blood Lactate Dehydrogenase Increased: 3 people, 23.08%

What are the existing conditions these people have? *

Primary Myelofibrosis (primary disorder of the bone marrow): 1 person, 7.69%
Pain: 1 person, 7.69%
Idiopathic Thrombocytopenic Purpura (Itp) (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 1 person, 7.69%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.69%
Blood Iron Decreased: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Cardizem and have Listless?

- Check whether Listless is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cardizem:

Cardizem (28,014 reports)

Listless treatments and more:

Listless (4,524 reports)

Browse all side effects of Cardizem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Listless:

Listless (456 drugs)

Browse all the conditions that are associated with Listless:

Listless (654 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on diltiazem hydrochloride (the active ingredients of Cardizem) and Cardizem (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.