Carpine and Hot flushes aggravated - a phase IV clinical study of FDA data

Summary:

Hot flushes aggravated is reported as a side effect among people who take Carpine (pilocarpine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Restasis, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Hot flushes aggravated when taking Carpine. It is created by eHealthMe based on reports of 5,521 people who have side effects when taking Carpine from the FDA, and is updated regularly.

What is Carpine?

Carpine has active ingredients of pilocarpine hydrochloride. eHealthMe is studying from 5,561 Carpine users. Check the latest studies of Carpine.

What is Hot flushes aggravated?

Hot flushes aggravated (sudden feelings of heat) is found to be associated with 1,520 drugs and 475 conditions by eHealthMe. Check the latest studies of Hot flushes aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

5,521 people reported to have side effects when taking Carpine.
Among them, 61 people (1.1%) have Hot flushes aggravated.

Could Carpine cause Hot flushes aggravated?

Among these 61 people:

How long have people been on Carpine when they have Hot flushes aggravated? *

What is the gender of people who have Hot flushes aggravated when taking Carpine? *

female: 96.3 %
male: 3.7 %

What is the age of people who have Hot flushes aggravated when taking Carpine? *

What are other drugs people take besides Carpine? *

What are other side effects people have besides Hot flushes aggravated? *

Diarrhea: 32 people, 52.46%
Itching: 30 people, 49.18%
Inflammation: 26 people, 42.62%
High Blood Pressure: 24 people, 39.34%
Platelet Count Increased: 23 people, 37.70%
Occult Blood (blood in the faeces that is not visibly apparent): 23 people, 37.70%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 23 people, 37.70%
Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 23 people, 37.70%
Spinal Osteoarthritis (joint cartilage loss in spine): 23 people, 37.70%
Joint Pain: 23 people, 37.70%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 31 people, 50.82%
Dry Mouth: 13 people, 21.31%
Stress And Anxiety: 12 people, 19.67%
High Blood Pressure: 11 people, 18.03%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 11 people, 18.03%
Psoriasis (immune-mediated disease that affects the skin): 10 people, 16.39%
Birth Control: 10 people, 16.39%
Gastric Ulcer (stomach ulcer): 9 people, 14.75%
Fibromyalgia (a long-term condition which causes pain all over the body): 7 people, 11.48%
Bipolar Disorder (mood disorder): 5 people, 8.20%

* Approximation only. Some reports may have incomplete information.

Do you take Carpine and have Hot flushes aggravated?

- Check whether Hot flushes aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Carpine:

Carpine (5,561 reports)

Browse all side effects of Carpine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hot flushes aggravated:

Hot flushes aggravated (1,521 drugs)

Browse all the conditions that are associated with Hot flushes aggravated:

Hot flushes aggravated (475 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pilocarpine hydrochloride (the active ingredients of Carpine) and Carpine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.