Catapres and Splenomegaly - a phase IV clinical study of FDA data

Summary:

Splenomegaly is reported as a side effect among people who take Catapres (clonidine hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Prednisone, and have Diabetes.

The phase IV clinical study analyzes which people have Splenomegaly when taking Catapres. It is created by eHealthMe based on reports of 6,532 people who have side effects when taking Catapres from the FDA, and is updated regularly.

What is Catapres?

Catapres has active ingredients of clonidine hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 6,680 Catapres users. Check the latest studies of Catapres.

What is Splenomegaly?

Splenomegaly (enlargement of spleen) is found to be associated with 1,113 drugs and 1,477 conditions by eHealthMe. Check the latest studies of Splenomegaly.

On Jul, 16, 2026

6,532 people reported to have side effects when taking Catapres.
Among them, 15 people (0.23%) have Splenomegaly.

Among these 15 people:

How long have people been on Catapres when they have Splenomegaly? *

What is the gender of people who have Splenomegaly when taking Catapres? *

female: 60 %
male: 40 %

What is the age of people who have Splenomegaly when taking Catapres? *

What are other drugs people take besides Catapres? *

What are other side effects people have besides Splenomegaly? *

Cardiac Failure Congestive: 12 people, 80.00%
Acute Kidney Failure: 11 people, 73.33%
Thrombocytopenia (decrease of platelets in blood): 11 people, 73.33%
Infection: 10 people, 66.67%
Headache (pain in head): 10 people, 66.67%
Hyperlipidaemia (presence of excess lipids in the blood): 10 people, 66.67%
Anaemia (lack of blood): 9 people, 60.00%
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 9 people, 60.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 53.33%
Pain: 8 people, 53.33%

What are the existing conditions these people have? *

Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 2 people, 13.33%
Diabetes: 2 people, 13.33%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 6.67%
Hypernatraemia (an abnormally high plasma concentration of sodium ions): 1 person, 6.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 6.67%
Depression: 1 person, 6.67%
Cellulitis (infection under the skin): 1 person, 6.67%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 1 person, 6.67%
Anaemia (lack of blood): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Catapres and have Splenomegaly?

- Check whether Splenomegaly is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Catapres:

Catapres (6,680 reports)

Splenomegaly treatments and more:

Splenomegaly (17,257 reports)

Browse all side effects of Catapres:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Splenomegaly:

Splenomegaly (1,113 drugs)

Browse all the conditions that are associated with Splenomegaly:

Splenomegaly (1,477 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on clonidine hydrochloride (the active ingredients of Catapres) and Catapres (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.