Cathflo activase and Fever - a phase IV clinical study of FDA data

Summary:

Fever is reported as a side effect among people who take Cathflo activase (alteplase), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Heparin, and have Nausea.

The phase IV clinical study analyzes which people have Fever when taking Cathflo activase. It is created by eHealthMe based on reports of 1,468 people who have side effects when taking Cathflo activase from the FDA, and is updated regularly.

What is Cathflo activase?

Cathflo activase has active ingredients of alteplase. eHealthMe is studying from 1,469 Cathflo activase users. Check the latest studies of Cathflo activase.

What is Fever?

Fever is found to be associated with 3,495 drugs and 6,198 conditions by eHealthMe. Check the latest studies of Fever.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

1,468 people reported to have side effects when taking Cathflo activase.
Among them, 63 people (4.29%) have Fever.

Among these 63 people:

How long have people been on Cathflo activase when they have Fever? *

What is the gender of people who have Fever when taking Cathflo activase? *

female: 48.39 %
male: 51.61 %

What is the age of people who have Fever when taking Cathflo activase? *

What are other drugs people take besides Cathflo activase? *

What are other side effects people have besides Fever? *

Headache (pain in head): 24 people, 38.10%
Fatigue (feeling of tiredness): 24 people, 38.10%
Cytokine Release Syndrome (immediate complication occurring with the use of anti-t cell antibody infusions): 20 people, 31.75%
Nausea (feeling of having an urge to vomit): 18 people, 28.57%
Chest Pain: 17 people, 26.98%
Thrombocytopenia (decrease of platelets in blood): 16 people, 25.40%
Diarrhea: 16 people, 25.40%
Hypotension (abnormally low blood pressure): 15 people, 23.81%
Haemoglobin Decreased: 15 people, 23.81%
Serum Ferritin Increased: 13 people, 20.63%

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 9 people, 14.29%
Pain: 8 people, 12.70%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 8 people, 12.70%
Indigestion: 8 people, 12.70%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 7 people, 11.11%
Constipation: 6 people, 9.52%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 5 people, 7.94%
Blood Culture Positive: 5 people, 7.94%
Pneumonia: 5 people, 7.94%
Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously): 4 people, 6.35%

* Approximation only. Some reports may have incomplete information.

Do you take Cathflo activase and have Fever?

- Check whether Fever is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cathflo activase:

Cathflo activase (1,469 reports)

Fever treatments and more:

Fever (498,666 reports)

Browse all side effects of Cathflo activase:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fever:

Fever (3,495 drugs)

Browse all the conditions that are associated with Fever:

Fever (6,198 conditions)

Related publications that referenced our studies

Schiller D, Maieron A, Sch?fl R, Donnerer J, "Drug fever due to a single dose of pantoprazole", Pharmacology, 2015 Jan .
Schiller D, Maieron A, Sch?fl R, Donnerer J, "Drug fever due to a single dose of pantoprazole", Pharmacology, 2015 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on alteplase (the active ingredients of Cathflo activase) and Cathflo activase (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.