Cefixime and Clostridium difficile colitis - a phase IV clinical study of FDA data

Summary:

Clostridium difficile colitis is reported as a side effect among people who take Cefixime (cefixime), especially for people who are male, 2-9 old, have been taking the drug for < 1 month also take Amlodipine, and have Thrombotic microangiopathy.

The phase IV clinical study analyzes which people have Clostridium difficile colitis when taking Cefixime. It is created by eHealthMe based on reports of 3,217 people who have side effects when taking Cefixime from the FDA, and is updated regularly.

What is Cefixime?

Cefixime has active ingredients of cefixime. eHealthMe is studying from 3,237 Cefixime users. Check the latest studies of Cefixime.

What is Clostridium difficile colitis?

Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection) is found to be associated with 1,042 drugs and 1,783 conditions by eHealthMe. Check the latest studies of Clostridium difficile colitis.

On Jul, 27, 2026

3,217 people reported to have side effects when taking Cefixime.
Among them, 23 people (0.71%) have Clostridium difficile colitis.

Could Cefixime cause Clostridium difficile colitis?

Among these 23 people:

How long have people been on Cefixime when they have Clostridium difficile colitis? *

What is the gender of people who have Clostridium difficile colitis when taking Cefixime? *

female: 36.36 %
male: 63.64 %

What is the age of people who have Clostridium difficile colitis when taking Cefixime? *

What are other drugs people take besides Cefixime? *

What are other side effects people have besides Clostridium difficile colitis? *

Fever: 9 people, 39.13%
Drug Ineffective: 5 people, 21.74%
Thrombotic Microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury): 4 people, 17.39%
Sepsis (a severe blood infection that can lead to organ failure and death): 3 people, 13.04%
Thrombocytopenia (decrease of platelets in blood): 2 people, 8.70%
Anaemia (lack of blood): 2 people, 8.70%
Blood Lactate Dehydrogenase Increased: 2 people, 8.70%
Diarrhea: 2 people, 8.70%
Disease Progression: 2 people, 8.70%
Disease Recurrence: 2 people, 8.70%

What are the existing conditions these people have? *

Thrombotic Microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury): 6 people, 26.09%
Metastases To Bone (cancer spreads to bone): 4 people, 17.39%
Neuroblastoma Recurrent (reoccurrence of a cancer that forms in your nerve tissue): 4 people, 17.39%
High Blood Pressure: 4 people, 17.39%
Bone Marrow Conditioning Regimen: 4 people, 17.39%
Urinary Tract Infection: 3 people, 13.04%
Infection: 3 people, 13.04%
Hypersensitivity: 2 people, 8.70%
Hyperkalemia (damage to or disease of the kidney): 2 people, 8.70%
Hypotension (abnormally low blood pressure): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

Do you take Cefixime and have Clostridium difficile colitis?

- Check whether Clostridium difficile colitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cefixime:

Cefixime (3,237 reports)

Browse all side effects of Cefixime:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Clostridium difficile colitis:

Clostridium difficile colitis (1,042 drugs)

Browse all the conditions that are associated with Clostridium difficile colitis:

Clostridium difficile colitis (1,783 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cefixime (the active ingredients of Cefixime) and Cefixime (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.