Cefotaxime and Type iv hypersensitivity reaction - a phase IV clinical study of FDA data

Summary:

Type iv hypersensitivity reaction is reported as a side effect among people who take Cefotaxime (cefotaxime sodium), especially for people who are female, 2-9 old, also take Ampicillin And Sulbactam, and have Pelvic abscess.

The phase IV clinical study analyzes which people have Type iv hypersensitivity reaction when taking Cefotaxime. It is created by eHealthMe based on reports of 7,540 people who have side effects when taking Cefotaxime from the FDA, and is updated regularly.

What is Cefotaxime?

Cefotaxime has active ingredients of cefotaxime sodium. eHealthMe is studying from 7,559 Cefotaxime users. Check the latest studies of Cefotaxime.

What is Type iv hypersensitivity reaction?

Type iv hypersensitivity reaction (delayed type hypersensitivity as the reaction takes two to three days to develop) is found to be associated with 198 drugs and 415 conditions by eHealthMe. Check the latest studies of Type iv hypersensitivity reaction.

On Jul, 06, 2026

7,540 people reported to have side effects when taking Cefotaxime.
Among them, 15 people (0.2%) have Type iv hypersensitivity reaction.

Could Cefotaxime cause Type iv hypersensitivity reaction?

Among these 15 people:

What is the gender of people who have Type iv hypersensitivity reaction when taking Cefotaxime? *

female: 76.92 %
male: 23.08 %

What is the age of people who have Type iv hypersensitivity reaction when taking Cefotaxime? *

What are other drugs people take besides Cefotaxime? *

Ampicillin And Sulbactam: 4 people, 26.67%
Sulfamethoxazole And Trimethoprim: 1 person, 6.67%
Nuvessa: 1 person, 6.67%
Clindamycin Phosphate: 1 person, 6.67%
Amoxicillin: 1 person, 6.67%

What are other side effects people have besides Type iv hypersensitivity reaction? *

Nausea And Vomiting: 5 people, 33.33%
Rashes (redness): 5 people, 33.33%
Drug Eruption (adverse drug reaction of the skin): 5 people, 33.33%
Fever: 5 people, 33.33%
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 4 people, 26.67%
Rash Maculo-Papular (red area on the skin that is covered with small confluent bumps): 2 people, 13.33%
Interleukin-2 Receptor Increased: 1 person, 6.67%
C-Reactive Protein Increased: 1 person, 6.67%
Drug Hypersensitivity: 1 person, 6.67%
High Blood Cholesterol: 1 person, 6.67%

What are the existing conditions these people have? *

Pelvic Abscess: 10 people, 66.67%
Appendicitis Perforated (perforated appendicitis is a condition in which an inflamed appendix bursts): 8 people, 53.33%
Douglas' Abscess (abscess in recto-uterine pouch): 5 people, 33.33%
Otitis (ear infection): 1 person, 6.67%
Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges): 1 person, 6.67%
Brucellosis (a bacterial disease typically affecting cattle and humans caused esp. by the bacteria brucella abortus): 1 person, 6.67%
Abdominal Abscess (collection of pus in abdomen): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Cefotaxime and have Type iv hypersensitivity reaction?

- Check whether Type iv hypersensitivity reaction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cefotaxime:

Cefotaxime (7,559 reports)

Browse all side effects of Cefotaxime:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Type iv hypersensitivity reaction:

Type iv hypersensitivity reaction (198 drugs)

Browse all the conditions that are associated with Type iv hypersensitivity reaction:

Type iv hypersensitivity reaction (415 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cefotaxime sodium (the active ingredients of Cefotaxime) and Cefotaxime (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.