Centrum and Ear buzzing - a phase IV clinical study of FDA data

Summary:

Ear buzzing is reported as a side effect among people who take Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Fish Oil, and have High blood cholesterol.

The phase IV clinical study analyzes which people have Ear buzzing when taking Centrum. It is created by eHealthMe based on reports of 33,642 people who have side effects when taking Centrum from the FDA, and is updated regularly.

What is Centrum?

Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 34,682 Centrum users. Check the latest studies of Centrum.

What is Ear buzzing?

Ear buzzing is found to be associated with 2,421 drugs and 3,078 conditions by eHealthMe. Check the latest studies of Ear buzzing.

On Dec, 05, 2025

33,642 people reported to have side effects when taking Centrum.
Among them, 241 people (0.72%) have Ear buzzing.

Among these 241 people:

How long have people been on Centrum when they have Ear buzzing? *

What is the gender of people who have Ear buzzing when taking Centrum? *

female: 67.67 %
male: 32.33 %

What is the age of people who have Ear buzzing when taking Centrum? *

What are other drugs people take besides Centrum? *

What are other side effects people have besides Ear buzzing? *

Dizziness: 66 people, 27.39%
Nausea (feeling of having an urge to vomit): 61 people, 25.31%
Headache (pain in head): 58 people, 24.07%
Stress And Anxiety: 57 people, 23.65%
Pain: 52 people, 21.58%
Insomnia (sleeplessness): 50 people, 20.75%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 47 people, 19.50%
Feeling Abnormal: 45 people, 18.67%
Fall: 44 people, 18.26%
Diarrhea: 43 people, 17.84%

What are the existing conditions these people have? *

High Blood Cholesterol: 59 people, 24.48%
High Blood Pressure: 30 people, 12.45%
Diabetes: 29 people, 12.03%
Depression: 22 people, 9.13%
Breast Cancer: 20 people, 8.30%
Insulin Resistance: 16 people, 6.64%
Hypersensitivity: 14 people, 5.81%
Stress And Anxiety: 12 people, 4.98%
Osteoporosis (bones weak and more likely to break): 12 people, 4.98%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 4.56%

* Approximation only. Some reports may have incomplete information.

Do you take Centrum and have Ear buzzing?

- Check whether Ear buzzing is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Centrum:

Centrum (34,682 reports)

Ear buzzing treatments and more:

Ear buzzing (58,539 reports)

How severe was Ear buzzing and when was it recovered:

Ear buzzing in Centrum

Expand to all the drugs that have ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e:

Ear buzzing and drugs with ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e (1,509 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Centrum side effects:

Centrum side effect: Nausea (feeling of having an urge to vomit) (2,325 reports)

Browse all side effects of Centrum:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Ear buzzing:

Browse all the drugs that are associated with Ear buzzing:

Ear buzzing (2,421 drugs)

Common conditions associated with Ear buzzing:

Depression: 3,635 reports
Antidepressant therapy: 3,623 reports
Hypertension: 2,663 reports
Htn: 2,652 reports
Arthritis - rheumatoid: 1,927 reports
Anxiety: 1,913 reports
Jitters: 1,912 reports
Pain exacerbated: 1,795 reports
Alternative medicine - pain relief: 1,778 reports
Blood cholesterol increased: 1,671 reports

Browse all the conditions that are associated with Ear buzzing:

Ear buzzing (3,078 conditions)

Drugs similar to Centrum and Ear buzzing :

Vitamin d side effect: Ear buzzing

How the study uses the data?

The study uses data from the FDA. It is based on ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e (the active ingredients of Centrum) and Centrum (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.