Centrum and Euphoric mood - a phase IV clinical study of FDA data

Summary:

Euphoric mood is reported as a side effect among people who take Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lyrica, and have High blood cholesterol.

The phase IV clinical study analyzes which people have Euphoric mood when taking Centrum. It is created by eHealthMe based on reports of 33,642 people who have side effects when taking Centrum from the FDA, and is updated regularly.

What is Centrum?

Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 34,686 Centrum users. Check the latest studies of Centrum.

What is Euphoric mood?

Euphoric mood (excessively happy but may become angry or irritable) is found to be associated with 638 drugs and 862 conditions by eHealthMe. Check the latest studies of Euphoric mood.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

33,642 people reported to have side effects when taking Centrum.
Among them, 12 people (0.04%) have Euphoric mood.

Among these 12 people:

How long have people been on Centrum when they have Euphoric mood? *

What is the gender of people who have Euphoric mood when taking Centrum? *

female: 91.67 %
male: 8.33 %

What is the age of people who have Euphoric mood when taking Centrum? *

What are other drugs people take besides Centrum? *

Lyrica: 4 people, 33.33%
Hydrochlorothiazide: 3 people, 25.00%
Calcium: 3 people, 25.00%
Horizant: 2 people, 16.67%
Amlodipine: 2 people, 16.67%
Sucralfate: 2 people, 16.67%
Singulair: 2 people, 16.67%
Calcium Acetate: 2 people, 16.67%
Chantix: 2 people, 16.67%
Citalopram Hydrobromide: 2 people, 16.67%

What are other side effects people have besides Euphoric mood? *

Dizziness: 6 people, 50.00%
Irritability: 5 people, 41.67%
Drowsiness: 4 people, 33.33%
Nightmares (unpleasant dreams): 3 people, 25.00%
Abnormal Dreams: 3 people, 25.00%
Thinking Abnormal: 3 people, 25.00%
Disturbance In Attention: 3 people, 25.00%
Anger: 3 people, 25.00%
Insomnia (sleeplessness): 2 people, 16.67%
Mania (a state of abnormally elevated or irritable mood): 2 people, 16.67%

What are the existing conditions these people have? *

High Blood Cholesterol: 4 people, 33.33%
High Blood Pressure: 3 people, 25.00%
Diabetes: 3 people, 25.00%
Neuropathy Peripheral (surface nerve damage): 3 people, 25.00%
Sleep Disorder: 3 people, 25.00%
Restless Leg Syndrome (a powerful urge to move your legs): 2 people, 16.67%
Quit Smoking: 2 people, 16.67%
Blood Pressure Abnormal: 2 people, 16.67%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 2 people, 16.67%
Thyroid Diseases: 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Centrum and have Euphoric mood?

- Check whether Euphoric mood is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Centrum:

Centrum (34,686 reports)

Euphoric mood treatments and more:

Euphoric mood (12,696 reports)

How severe was Euphoric mood and when was it recovered:

Euphoric mood in Centrum

Expand to all the drugs that have ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e:

Euphoric mood and drugs with ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e (181 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Centrum:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Euphoric mood:

Euphoric mood (638 drugs)

Browse all the conditions that are associated with Euphoric mood:

Euphoric mood (862 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e (the active ingredients of Centrum) and Centrum (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.