Centrum and Hypercoagulation - a phase IV clinical study of FDA data

Summary:

Hypercoagulation is reported as a side effect among people who take Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e), especially for people who are female, 60+ old, also take Protonix, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Hypercoagulation when taking Centrum. It is created by eHealthMe based on reports of 33,642 people who have side effects when taking Centrum from the FDA, and is updated regularly.

What is Centrum?

Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 34,685 Centrum users. Check the latest studies of Centrum.

What is Hypercoagulation?

Hypercoagulation (increased tendency for clotting of the blood) is found to be associated with 404 drugs and 536 conditions by eHealthMe. Check the latest studies of Hypercoagulation.

On May, 01, 2026

33,642 people reported to have side effects when taking Centrum.
Among them, 15 people (0.04%) have Hypercoagulation.

Among these 15 people:

What is the gender of people who have Hypercoagulation when taking Centrum? *

female: 100 %
male: 0.0 %

What is the age of people who have Hypercoagulation when taking Centrum? *

What are other drugs people take besides Centrum? *

What are other side effects people have besides Hypercoagulation? *

Weakness: 13 people, 86.67%
Dehydration (dryness resulting from the removal of water): 13 people, 86.67%
Pneumonia: 10 people, 66.67%
Hypokalemia (low potassium): 10 people, 66.67%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 10 people, 66.67%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 10 people, 66.67%
Cardiac Failure Congestive: 9 people, 60.00%
Nausea (feeling of having an urge to vomit): 9 people, 60.00%
Pleural Effusion (water on the lungs): 9 people, 60.00%
Diarrhea: 9 people, 60.00%

What are the existing conditions these people have? *

Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 9 people, 60.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 26.67%
Weakness: 2 people, 13.33%
Reflux Gastritis (a condition in which the lining of a person's stomach becomes inflamed as a result of exposure to bile): 2 people, 13.33%
Pain: 2 people, 13.33%
Neuropathy Peripheral (surface nerve damage): 2 people, 13.33%
Insomnia (sleeplessness): 2 people, 13.33%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 13.33%
Depression: 2 people, 13.33%
Back Pain: 2 people, 13.33%

* Approximation only. Some reports may have incomplete information.

Do you take Centrum and have Hypercoagulation?

- Check whether Hypercoagulation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Centrum:

Centrum (34,685 reports)

Hypercoagulation treatments and more:

Hypercoagulation (4,011 reports)

How severe was Hypercoagulation and when was it recovered:

Hypercoagulation in Centrum

Expand to all the drugs that have ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e:

Hypercoagulation and drugs with ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e (87 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Centrum:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypercoagulation:

Hypercoagulation (404 drugs)

Browse all the conditions that are associated with Hypercoagulation:

Hypercoagulation (536 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e (the active ingredients of Centrum) and Centrum (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.