Centrum and Oesophageal candidiasis - a phase IV clinical study of FDA data

Summary:

Oesophageal candidiasis is reported as a side effect among people who take Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Vitamin C, and have Asthma.

The phase IV clinical study analyzes which people have Oesophageal candidiasis when taking Centrum. It is created by eHealthMe based on reports of 33,642 people who have side effects when taking Centrum from the FDA, and is updated regularly.

What is Centrum?

Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 34,686 Centrum users. Check the latest studies of Centrum.

What is Oesophageal candidiasis?

Oesophageal candidiasis (fungal infection of oesophagus) is found to be associated with 664 drugs and 695 conditions by eHealthMe. Check the latest studies of Oesophageal candidiasis.

On Jul, 08, 2026

33,642 people reported to have side effects when taking Centrum.
Among them, 12 people (0.04%) have Oesophageal candidiasis.

Could Centrum cause Oesophageal candidiasis?

Among these 12 people:

How long have people been on Centrum when they have Oesophageal candidiasis? *

What is the gender of people who have Oesophageal candidiasis when taking Centrum? *

female: 72.73 %
male: 27.27 %

What is the age of people who have Oesophageal candidiasis when taking Centrum? *

What are other drugs people take besides Centrum? *

What are other side effects people have besides Oesophageal candidiasis? *

Nausea (feeling of having an urge to vomit): 6 people, 50.00%
Oral Candidiasis (fungal infection of mouth): 6 people, 50.00%
Fever: 5 people, 41.67%
Urinary Tract Infection: 5 people, 41.67%
Abdominal Pain: 4 people, 33.33%
Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 4 people, 33.33%
Oedema Peripheral (superficial swelling): 4 people, 33.33%
Sinusitis (inflammation of sinus): 4 people, 33.33%
Dizziness: 4 people, 33.33%
Neck Pain: 4 people, 33.33%

What are the existing conditions these people have? *

Asthma: 4 people, 33.33%
Wheezing (a high-pitched whistling sound made while you breath): 3 people, 25.00%
Swelling: 3 people, 25.00%
Chest Pain: 3 people, 25.00%
Constipation: 3 people, 25.00%
Cough: 3 people, 25.00%
Fungal Infection: 3 people, 25.00%
Pain: 3 people, 25.00%
Infection: 3 people, 25.00%
Nausea (feeling of having an urge to vomit): 3 people, 25.00%

* Approximation only. Some reports may have incomplete information.

Do you take Centrum and have Oesophageal candidiasis?

- Check whether Oesophageal candidiasis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Centrum:

Centrum (34,686 reports)

Oesophageal candidiasis treatments and more:

Oesophageal candidiasis (5,833 reports)

How severe was Oesophageal candidiasis and when was it recovered:

Oesophageal candidiasis in Centrum

Expand to all the drugs that have ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e:

Oesophageal candidiasis and drugs with ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Centrum:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Oesophageal candidiasis:

Oesophageal candidiasis (664 drugs)

Browse all the conditions that are associated with Oesophageal candidiasis:

Oesophageal candidiasis (695 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e (the active ingredients of Centrum) and Centrum (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.