Centrum and Onychalgia - a phase IV clinical study of FDA data

Summary:

Onychalgia is reported as a side effect among people who take Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e), especially for people who are male, 60+ old, also take Dexamethasone, and have Metastases to bone.

The phase IV clinical study analyzes which people have Onychalgia when taking Centrum. It is created by eHealthMe based on reports of 33,642 people who have side effects when taking Centrum from the FDA, and is updated regularly.

What is Centrum?

Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 34,686 Centrum users. Check the latest studies of Centrum.

What is Onychalgia?

Onychalgia (nail biting) is found to be associated with 250 drugs and 275 conditions by eHealthMe. Check the latest studies of Onychalgia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

33,642 people reported to have side effects when taking Centrum.
Among them, 11 people (0.03%) have Onychalgia.

Among these 11 people:

What is the gender of people who have Onychalgia when taking Centrum? *

female: 36.36 %
male: 63.64 %

What is the age of people who have Onychalgia when taking Centrum? *

What are other drugs people take besides Centrum? *

What are other side effects people have besides Onychalgia? *

Dyspnea (difficult or laboured breathing): 9 people, 81.82%
Nail Discoloration: 9 people, 81.82%
Loose Tooth: 9 people, 81.82%
Fungal Nail Infection: 9 people, 81.82%
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 8 people, 72.73%
Constipation: 8 people, 72.73%
Inflammation: 8 people, 72.73%
Weakness: 8 people, 72.73%
Nail Dystrophy (bed formation of nail): 7 people, 63.64%
Nail Hypertrophy (overgrowth or thickening of the nail): 7 people, 63.64%

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 7 people, 63.64%
High Blood Cholesterol: 3 people, 27.27%
Weight Decreased: 2 people, 18.18%
Thyroid Diseases: 2 people, 18.18%
Renal Disorder (kidney disease): 2 people, 18.18%
Renal Cancer Metastatic (cancer of kidney spreads to other part): 2 people, 18.18%
Pain: 2 people, 18.18%
Nausea (feeling of having an urge to vomit): 2 people, 18.18%
High Blood Pressure: 2 people, 18.18%
Diabetes: 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

Do you take Centrum and have Onychalgia?

- Check whether Onychalgia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Centrum:

Centrum (34,686 reports)

Onychalgia treatments and more:

Onychalgia (1,231 reports)

How severe was Onychalgia and when was it recovered:

Onychalgia in Centrum

Expand to all the drugs that have ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e:

Onychalgia and drugs with ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e (57 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Centrum:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Onychalgia:

Onychalgia (250 drugs)

Browse all the conditions that are associated with Onychalgia:

Onychalgia (275 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e (the active ingredients of Centrum) and Centrum (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.