Centrum and Thinking abnormal - a phase IV clinical study of FDA data

Summary:

Thinking abnormal is reported as a side effect among people who take Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e), especially for people who are female, 60+ old, also take Melatonin, and have Pain.

The phase IV clinical study analyzes which people have Thinking abnormal when taking Centrum. It is created by eHealthMe based on reports of 33,642 people who have side effects when taking Centrum from the FDA, and is updated regularly.

What is Centrum?

Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 34,682 Centrum users. Check the latest studies of Centrum.

What is Thinking abnormal?

Thinking abnormal is found to be associated with 1,135 drugs and 1,176 conditions by eHealthMe. Check the latest studies of Thinking abnormal.

On Dec, 21, 2025

33,642 people reported to have side effects when taking Centrum.
Among them, 65 people (0.19%) have Thinking abnormal.

Among these 65 people:

* Approximation only. Some reports may have incomplete information.

Do you take Centrum and have Thinking abnormal?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Centrum:

Centrum (34,682 reports)

Thinking abnormal treatments and more:

Thinking abnormal (22,435 reports)

How severe was Thinking abnormal and when was it recovered:

Thinking abnormal in Centrum

Expand to all the drugs that have ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e:

Thinking abnormal and drugs with ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e (530 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Centrum side effects:

Centrum side effect: Nausea (feeling of having an urge to vomit) (2,325 reports)
Centrum side effect: Fall (1,850 reports)

Browse all side effects of Centrum:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Thinking abnormal:

Browse all the drugs that are associated with Thinking abnormal:

Thinking abnormal (1,135 drugs)

Common conditions associated with Thinking abnormal:

Depression: 2,057 reports
Antidepressant therapy: 2,037 reports
Pain: 1,202 reports
Alternative medicine - pain relief: 1,172 reports
Anxiety: 1,067 reports
Stress and anxiety: 1,066 reports
Tobacco user: 798 reports
Ms: 792 reports
Sleeping: 735 reports
Schizophrenia: 622 reports

Browse all the conditions that are associated with Thinking abnormal:

Thinking abnormal (1,176 conditions)

Drugs similar to Centrum and Thinking abnormal :

Vitamin d side effect: Thinking abnormal

How the study uses the data?

The study uses data from the FDA. It is based on ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e (the active ingredients of Centrum) and Centrum (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.