Chestnut and Fall - a phase IV clinical study of FDA data

Summary:

Fall is reported as a side effect among people who take Chestnut (horse chestnut), especially for people who are female, 40-49 old, have been taking the drug for 10+ years also take Flaxseed, and have High blood pressure.

The phase IV clinical study analyzes which people have Fall when taking Chestnut. It is created by eHealthMe based on reports of 517 people who have side effects when taking Chestnut from the FDA, and is updated regularly.

What is Chestnut?

Chestnut has active ingredients of horse chestnut. eHealthMe is studying from 538 Chestnut users. Check the latest studies of Chestnut.

What is Fall?

Fall is found to be associated with 3,273 drugs and 3,757 conditions by eHealthMe. Check the latest studies of Fall.

On Jun, 20, 2026

517 people reported to have side effects when taking Chestnut.
Among them, 13 people (2.51%) have Fall.

Among these 13 people:

How long have people been on Chestnut when they have Fall? *

What is the gender of people who have Fall when taking Chestnut? *

female: 100 %
male: 0.0 %

What is the age of people who have Fall when taking Chestnut? *

What are other drugs people take besides Chestnut? *

What are other side effects people have besides Fall? *

Joint Pain: 7 people, 53.85%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 7 people, 53.85%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 46.15%
Uterine Leiomyoma (uterine benign tumour derived from smooth muscle): 5 people, 38.46%
Restless Leg Syndrome (a powerful urge to move your legs): 5 people, 38.46%
Constipation: 5 people, 38.46%
Cervical Dysplasia (abnormal changes in the cells on the surface of the cervix): 5 people, 38.46%
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 5 people, 38.46%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 5 people, 38.46%
Angiopathy (generic term for a disease of the blood vessels): 5 people, 38.46%

What are the existing conditions these people have? *

High Blood Pressure: 7 people, 53.85%
High Blood Cholesterol: 6 people, 46.15%
Osteopenia (a condition where bone mineral density is lower than normal): 5 people, 38.46%
Herpes Simplex (herpes simplex is a common viral infection): 5 people, 38.46%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 30.77%
Cardiovascular Insufficiency (inadequate functioning of heart): 3 people, 23.08%
Gastritis (inflammation of stomach): 3 people, 23.08%
Varicose Vein (veins that have become enlarged and tortuous): 2 people, 15.38%
Thyroid Diseases: 2 people, 15.38%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 15.38%

* Approximation only. Some reports may have incomplete information.

Do you take Chestnut and have Fall?

- Check whether Fall is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Chestnut:

Chestnut (538 reports)

Fall treatments and more:

Fall (403,513 reports)

Browse all side effects of Chestnut:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fall:

Fall (3,273 drugs)

Browse all the conditions that are associated with Fall:

Fall (3,757 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on horse chestnut (the active ingredients of Chestnut) and Chestnut (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.