Chlorhexidine gluconate and Hypoacusis - a phase IV clinical study of FDA data

Summary:

Hypoacusis is reported as a side effect among people who take Chlorhexidine gluconate (chlorhexidine gluconate), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Dexamethasone, and have Metastases to bone.

The phase IV clinical study analyzes which people have Hypoacusis when taking Chlorhexidine gluconate. It is created by eHealthMe based on reports of 8,183 people who have side effects when taking Chlorhexidine gluconate from the FDA, and is updated regularly.

What is Chlorhexidine gluconate?

Chlorhexidine gluconate has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 8,233 Chlorhexidine gluconate users. Check the latest studies of Chlorhexidine gluconate.

What is Hypoacusis?

Hypoacusis (loss of hearing) is found to be associated with 1,333 drugs and 1,187 conditions by eHealthMe. Check the latest studies of Hypoacusis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 20, 2026

8,183 people reported to have side effects when taking Chlorhexidine gluconate.
Among them, 42 people (0.51%) have Hypoacusis.

Could Chlorhexidine gluconate cause Hypoacusis?

Among these 42 people:

How long have people been on Chlorhexidine gluconate when they have Hypoacusis? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hypoacusis when taking Chlorhexidine gluconate? *

  • female: 33.33 %
  • male: 66.67 %

What is the age of people who have Hypoacusis when taking Chlorhexidine gluconate? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 3.03 %
  • 60+: 96.97 %

What are other drugs people take besides Chlorhexidine gluconate? *

  1. Dexamethasone: 29 people, 69.05%
  2. Zometa: 22 people, 52.38%
  3. Furosemide: 20 people, 47.62%
  4. Aranesp: 19 people, 45.24%
  5. Aredia: 18 people, 42.86%
  6. Neurontin: 16 people, 38.10%
  7. Protonix: 15 people, 35.71%
  8. Folic Acid: 15 people, 35.71%
  9. Gabapentin: 15 people, 35.71%
  10. Lipitor: 15 people, 35.71%

What are other side effects people have besides Hypoacusis? *

  1. Nausea (feeling of having an urge to vomit): 26 people, 61.90%
  2. Constipation: 25 people, 59.52%
  3. Dyspnea (difficult or laboured breathing): 24 people, 57.14%
  4. Stress And Anxiety: 24 people, 57.14%
  5. Injury: 24 people, 57.14%
  6. Pain: 24 people, 57.14%
  7. Impaired Healing: 23 people, 54.76%
  8. Swelling: 23 people, 54.76%
  9. Osteonecrosis Of Jaw (death of bone of jaw): 23 people, 54.76%
  10. Osteomyelitis (infection of bone): 23 people, 54.76%

What are the existing conditions these people have? *

  1. Metastases To Bone (cancer spreads to bone): 9 people, 21.43%
  2. Multiple Myeloma (cancer of the plasma cells): 8 people, 19.05%
  3. Urinary Tract Infection: 5 people, 11.90%
  4. Small Cell Lung Cancer Extensive Stage (small cell lung cancer that has spread (metastasized) to other regions of the body such as another lobe of the lung or the brain): 5 people, 11.90%
  5. Neoplasm Malignant (cancer tumour): 5 people, 11.90%
  6. Mouth Ulcers: 5 people, 11.90%
  7. Primary Myelofibrosis (primary disorder of the bone marrow): 2 people, 4.76%
  8. Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 2 people, 4.76%
  9. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 2.38%
  10. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 2.38%

* Approximation only. Some reports may have incomplete information.

Do you take Chlorhexidine gluconate and have Hypoacusis?

- Check whether Hypoacusis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Chlorhexidine gluconate:

Hypoacusis treatments and more:

How severe was Hypoacusis and when was it recovered:

Expand to all the drugs that have ingredients of chlorhexidine gluconate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Chlorhexidine gluconate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypoacusis:

Browse all the conditions that are associated with Hypoacusis:


How the study uses the data?

The study uses data from the FDA. It is based on chlorhexidine gluconate (the active ingredients of Chlorhexidine gluconate) and Chlorhexidine gluconate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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