Chlorhexidine gluconate and Procedural pain - a phase IV clinical study of FDA data

Summary:

Procedural pain is reported as a side effect among people who take Chlorhexidine gluconate (chlorhexidine gluconate), especially for people who are female, 60+ old, also take Lorazepam, and have Breast cancer.

The phase IV clinical study analyzes which people have Procedural pain when taking Chlorhexidine gluconate. It is created by eHealthMe based on reports of 8,183 people who have side effects when taking Chlorhexidine gluconate from the FDA, and is updated regularly.

What is Chlorhexidine gluconate?

Chlorhexidine gluconate has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 8,233 Chlorhexidine gluconate users. Check the latest studies of Chlorhexidine gluconate.

What is Procedural pain?

Procedural pain is found to be associated with 992 drugs and 926 conditions by eHealthMe. Check the latest studies of Procedural pain.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

8,183 people reported to have side effects when taking Chlorhexidine gluconate.
Among them, 31 people (0.38%) have Procedural pain.

Could Chlorhexidine gluconate cause Procedural pain?

Among these 31 people:

What is the gender of people who have Procedural pain when taking Chlorhexidine gluconate? *

female: 96.67 %
male: 3.33 %

What is the age of people who have Procedural pain when taking Chlorhexidine gluconate? *

What are other drugs people take besides Chlorhexidine gluconate? *

Lorazepam: 22 people, 70.97%
Betamethasone Valerate: 21 people, 67.74%
Bactrim: 19 people, 61.29%
Prednisone: 19 people, 61.29%
Zyrtec: 18 people, 58.06%
Reglan: 18 people, 58.06%
Percocet: 18 people, 58.06%
Fosamax: 18 people, 58.06%
Elidel: 18 people, 58.06%
Nolvadex: 18 people, 58.06%

What are other side effects people have besides Procedural pain? *

Tooth Fracture: 24 people, 77.42%
Rashes (redness): 19 people, 61.29%
Weight Decreased: 18 people, 58.06%
Gums - Swollen: 18 people, 58.06%
Pain In Extremity: 18 people, 58.06%
Pain: 18 people, 58.06%
Osteomyelitis (infection of bone): 18 people, 58.06%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 18 people, 58.06%
Oral Discomfort (pain or irritation in mouth): 18 people, 58.06%
Impaired Healing: 18 people, 58.06%

What are the existing conditions these people have? *

Breast Cancer: 20 people, 64.52%
Metastases To Bone (cancer spreads to bone): 18 people, 58.06%
Stress And Anxiety: 17 people, 54.84%
Bone Pain: 17 people, 54.84%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 17 people, 54.84%
Breast Cancer Metastatic: 7 people, 22.58%
Immunodeficiency Common Variable: 6 people, 19.35%
Primary Immunodeficiency Syndrome: 5 people, 16.13%
Cellulitis (infection under the skin): 3 people, 9.68%
Dry Skin: 3 people, 9.68%

* Approximation only. Some reports may have incomplete information.

Do you take Chlorhexidine gluconate and have Procedural pain?

- Check whether Procedural pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Chlorhexidine gluconate:

Chlorhexidine gluconate (8,233 reports)

Procedural pain treatments and more:

Procedural pain (36,096 reports)

Browse all side effects of Chlorhexidine gluconate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Procedural pain:

Procedural pain (992 drugs)

Browse all the conditions that are associated with Procedural pain:

Procedural pain (926 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on chlorhexidine gluconate (the active ingredients of Chlorhexidine gluconate) and Chlorhexidine gluconate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.