Chlorthalidone and Enlarged heart - a phase IV clinical study of FDA data

Summary:

Enlarged heart is reported as a side effect among people who take Chlorthalidone (chlorthalidone), especially for people who are female, 60+ old, also take Lisinopril, and have Cardiac disorder.

The phase IV clinical study analyzes which people have Enlarged heart when taking Chlorthalidone. It is created by eHealthMe based on reports of 11,957 people who have side effects when taking Chlorthalidone from the FDA, and is updated regularly.

What is Chlorthalidone?

Chlorthalidone has active ingredients of chlorthalidone. It is often used in high blood pressure. eHealthMe is studying from 12,482 Chlorthalidone users. Check the latest studies of Chlorthalidone.

What is Enlarged heart?

Enlarged heart is found to be associated with 1,456 drugs and 1,663 conditions by eHealthMe. Check the latest studies of Enlarged heart.

On Jul, 11, 2026

11,957 people reported to have side effects when taking Chlorthalidone.
Among them, 18 people (0.15%) have Enlarged heart.

Could Chlorthalidone cause Enlarged heart?

Among these 18 people:

What is the gender of people who have Enlarged heart when taking Chlorthalidone? *

female: 70.59 %
male: 29.41 %

What is the age of people who have Enlarged heart when taking Chlorthalidone? *

What are other drugs people take besides Chlorthalidone? *

What are other side effects people have besides Enlarged heart? *

Fatigue (feeling of tiredness): 7 people, 38.89%
Weight Increased: 6 people, 33.33%
Hypotension (abnormally low blood pressure): 6 people, 33.33%
Rectal Haemorrhage (bleeding from anus): 4 people, 22.22%
Blood Potassium Decreased: 4 people, 22.22%
Diarrhea: 4 people, 22.22%
Diverticulum Intestinal (a pouch that is attached to the first part of the small intestine): 4 people, 22.22%
Haematochezia (passage of stools containing blood): 4 people, 22.22%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 4 people, 22.22%
Headache (pain in head): 4 people, 22.22%

What are the existing conditions these people have? *

Insomnia (sleeplessness): 3 people, 16.67%
Immunodeficiency Common Variable: 3 people, 16.67%
Glucose Tolerance Impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis): 3 people, 16.67%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 3 people, 16.67%
Cardiac Disorder: 3 people, 16.67%
Trigeminal Neuralgia (a painful condition of the nerve responsible for most facial sensation): 1 person, 5.56%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 5.56%
Renal Disorder (kidney disease): 1 person, 5.56%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 5.56%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Chlorthalidone and have Enlarged heart?

- Check whether Enlarged heart is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Chlorthalidone:

Chlorthalidone (12,482 reports)

Enlarged heart treatments and more:

Enlarged heart (20,022 reports)

Browse all side effects of Chlorthalidone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Enlarged heart:

Enlarged heart (1,456 drugs)

Browse all the conditions that are associated with Enlarged heart:

Enlarged heart (1,663 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on chlorthalidone (the active ingredients of Chlorthalidone) and Chlorthalidone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.