Chlorzoxazone and Intervertebral disc degeneration - a phase IV clinical study of FDA data

Summary:

Intervertebral disc degeneration is reported as a side effect among people who take Chlorzoxazone (chlorzoxazone), especially for people who are female, 60+ old, also take Cymbalta, and have Metastatic neoplasm.

The phase IV clinical study analyzes which people have Intervertebral disc degeneration when taking Chlorzoxazone. It is created by eHealthMe based on reports of 1,743 people who have side effects when taking Chlorzoxazone from the FDA, and is updated regularly.

What is Chlorzoxazone?

Chlorzoxazone has active ingredients of chlorzoxazone. It is often used in muscle spasms. eHealthMe is studying from 1,836 Chlorzoxazone users. Check the latest studies of Chlorzoxazone.

What is Intervertebral disc degeneration?

Intervertebral disc degeneration (spinal disc degeneration) is found to be associated with 1,316 drugs and 1,496 conditions by eHealthMe. Check the latest studies of Intervertebral disc degeneration.

On Jul, 08, 2026

1,743 people reported to have side effects when taking Chlorzoxazone.
Among them, 24 people (1.38%) have Intervertebral disc degeneration.

Could Chlorzoxazone cause Intervertebral disc degeneration?

Among these 24 people:

What is the gender of people who have Intervertebral disc degeneration when taking Chlorzoxazone? *

female: 91.67 %
male: 8.33 %

What is the age of people who have Intervertebral disc degeneration when taking Chlorzoxazone? *

What are other drugs people take besides Chlorzoxazone? *

Cymbalta: 21 people, 87.50%
Fluconazole: 19 people, 79.17%
Crestor: 19 people, 79.17%
Proair Hfa: 18 people, 75.00%
Fosamax: 16 people, 66.67%
Glucophage: 15 people, 62.50%
Mucinex: 15 people, 62.50%
Metolazone: 15 people, 62.50%
Metformin Hydrochloride: 15 people, 62.50%
Meloxicam: 15 people, 62.50%

What are other side effects people have besides Intervertebral disc degeneration? *

Osteopenia (a condition where bone mineral density is lower than normal): 20 people, 83.33%
Rashes (redness): 19 people, 79.17%
Asthma: 18 people, 75.00%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 18 people, 75.00%
Seasonal Allergy (allergic condition due to certain season): 18 people, 75.00%
Depression: 17 people, 70.83%
Fall: 16 people, 66.67%
Kidney Stones: 16 people, 66.67%
Osteoporosis (bones weak and more likely to break): 16 people, 66.67%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 16 people, 66.67%

What are the existing conditions these people have? *

Breast Cancer Metastatic: 15 people, 62.50%
Metastatic Neoplasm (spreadable cancer tumour): 15 people, 62.50%
Hypersensitivity: 12 people, 50.00%
Diabetes: 12 people, 50.00%
Immunodeficiency Common Variable: 4 people, 16.67%
Stress And Anxiety: 1 person, 4.17%
Encephalitis Viral (inflammation of the brain due to viral infection): 1 person, 4.17%
Back Injury: 1 person, 4.17%
Cardiac Disorder: 1 person, 4.17%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Chlorzoxazone and have Intervertebral disc degeneration?

- Check whether Intervertebral disc degeneration is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Chlorzoxazone:

Chlorzoxazone (1,836 reports)

Browse all side effects of Chlorzoxazone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Intervertebral disc degeneration:

Intervertebral disc degeneration (1,316 drugs)

Browse all the conditions that are associated with Intervertebral disc degeneration:

Intervertebral disc degeneration (1,496 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on chlorzoxazone (the active ingredients of Chlorzoxazone) and Chlorzoxazone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.