Cialis and Toothaches - a phase IV clinical study of FDA data

Summary:

Toothaches is reported as a side effect among people who take Cialis (tadalafil), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Folic Acid, and have Hypercalcaemia.

The phase IV clinical study analyzes which people have Toothaches when taking Cialis. It is created by eHealthMe based on reports of 26,412 people who have side effects when taking Cialis from the FDA, and is updated regularly.

What is Cialis?

Cialis has active ingredients of tadalafil. It is often used in erection problems. eHealthMe is studying from 28,532 Cialis users. Check the latest studies of Cialis.

What is Toothaches?

Toothaches (tooth pain) is found to be associated with 1,318 drugs and 1,605 conditions by eHealthMe. Check the latest studies of Toothaches.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

26,412 people reported to have side effects when taking Cialis.
Among them, 43 people (0.16%) have Toothaches.

Among these 43 people:

How long have people been on Cialis when they have Toothaches? *

What is the gender of people who have Toothaches when taking Cialis? *

female: 60.53 %
male: 39.47 %

What is the age of people who have Toothaches when taking Cialis? *

What are other drugs people take besides Cialis? *

What are other side effects people have besides Toothaches? *

Pain In Extremity: 32 people, 74.42%
Weakness: 30 people, 69.77%
Back Pain: 30 people, 69.77%
Gingival Pain (gum pain): 28 people, 65.12%
Joint Pain: 28 people, 65.12%
Stress And Anxiety: 28 people, 65.12%
Tooth Abscess (pus formation in tooth): 27 people, 62.79%
Fever: 27 people, 62.79%
Spinal Osteoarthritis (joint cartilage loss in spine): 26 people, 60.47%
Oedema Peripheral (superficial swelling): 26 people, 60.47%

What are the existing conditions these people have? *

Breast Cancer: 23 people, 53.49%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 23 people, 53.49%
Breast Cancer Metastatic: 22 people, 51.16%
Metastases To Bone (cancer spreads to bone): 4 people, 9.30%
Pain: 4 people, 9.30%
Diabetes: 3 people, 6.98%
High Blood Cholesterol: 3 people, 6.98%
Headache (pain in head): 3 people, 6.98%
Sleep Disorder: 3 people, 6.98%
Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 3 people, 6.98%

* Approximation only. Some reports may have incomplete information.

Do you take Cialis and have Toothaches?

- Check whether Toothaches is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cialis:

Cialis (28,532 reports)

Toothaches treatments and more:

Toothaches (28,231 reports)

Browse all side effects of Cialis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Toothaches:

Toothaches (1,318 drugs)

Browse all the conditions that are associated with Toothaches:

Toothaches (1,605 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tadalafil (the active ingredients of Cialis) and Cialis (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.