Cimetidine and Cerebral atrophy - a phase IV clinical study of FDA data

Summary:

Cerebral atrophy is reported as a side effect among people who take Cimetidine (cimetidine), especially for people who are male, 60+ old, also take Citalopram Hydrobromide, and have Gastroduodenal ulcer.

The phase IV clinical study analyzes which people have Cerebral atrophy when taking Cimetidine. It is created by eHealthMe based on reports of 10,379 people who have side effects when taking Cimetidine from the FDA, and is updated regularly.

What is Cimetidine?

Cimetidine has active ingredients of cimetidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 10,531 Cimetidine users. Check the latest studies of Cimetidine.

What is Cerebral atrophy?

Cerebral atrophy (decrement in size of brain) is found to be associated with 807 drugs and 856 conditions by eHealthMe. Check the latest studies of Cerebral atrophy.

On Jul, 05, 2026

10,379 people reported to have side effects when taking Cimetidine.
Among them, 18 people (0.17%) have Cerebral atrophy.

Could Cimetidine cause Cerebral atrophy?

Among these 18 people:

What is the gender of people who have Cerebral atrophy when taking Cimetidine? *

female: 16.67 %
male: 83.33 %

What is the age of people who have Cerebral atrophy when taking Cimetidine? *

What are other drugs people take besides Cimetidine? *

Elavil: 4 people, 22.22%
Citalopram Hydrobromide: 4 people, 22.22%
Tagamet: 3 people, 16.67%
Ticlopidine Hydrochloride: 3 people, 16.67%
Nexium: 3 people, 16.67%
Quetiapine Fumarate: 3 people, 16.67%
Clonazepam: 3 people, 16.67%
Risperdal: 3 people, 16.67%
Risperdal Consta: 3 people, 16.67%
Neurontin: 3 people, 16.67%

What are other side effects people have besides Cerebral atrophy? *

Nausea (feeling of having an urge to vomit): 6 people, 33.33%
Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time): 5 people, 27.78%
High Blood Pressure: 5 people, 27.78%
Agitation (state of anxiety or nervous excitement): 5 people, 27.78%
Blood Glucose Increased: 5 people, 27.78%
Hyperreflexia (overactive or over responsive reflexes): 5 people, 27.78%
Fatigue (feeling of tiredness): 4 people, 22.22%
Electroencephalogram Abnormal: 4 people, 22.22%
Depression: 4 people, 22.22%
Weakness: 4 people, 22.22%

What are the existing conditions these people have? *

Gastroduodenal Ulcer: 5 people, 27.78%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 16.67%
Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 3 people, 16.67%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 11.11%
Type 2 Diabetes: 1 person, 5.56%
Herpes Zoster: 1 person, 5.56%
Depression: 1 person, 5.56%
Depressive Symptom: 1 person, 5.56%
Headache (pain in head): 1 person, 5.56%
Hepatitis C: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Cimetidine and have Cerebral atrophy?

- Check whether Cerebral atrophy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cimetidine:

Cimetidine (10,531 reports)

Browse all side effects of Cimetidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cerebral atrophy:

Cerebral atrophy (807 drugs)

Browse all the conditions that are associated with Cerebral atrophy:

Cerebral atrophy (856 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cimetidine (the active ingredients of Cimetidine) and Cimetidine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.