Cimetidine and Osteolysis - a phase IV clinical study of FDA data

Summary:

Osteolysis is reported as a side effect among people who take Cimetidine (cimetidine), especially for people who are female, 50-59 old, also take Zometa, and have Breast cancer.

The phase IV clinical study analyzes which people have Osteolysis when taking Cimetidine. It is created by eHealthMe based on reports of 10,379 people who have side effects when taking Cimetidine from the FDA, and is updated regularly.

What is Cimetidine?

Cimetidine has active ingredients of cimetidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 10,531 Cimetidine users. Check the latest studies of Cimetidine.

What is Osteolysis?

Osteolysis (dissolution of bone) is found to be associated with 689 drugs and 409 conditions by eHealthMe. Check the latest studies of Osteolysis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

10,379 people reported to have side effects when taking Cimetidine.
Among them, 38 people (0.37%) have Osteolysis.

Among these 38 people:

What is the gender of people who have Osteolysis when taking Cimetidine? *

female: 91.67 %
male: 8.33 %

What is the age of people who have Osteolysis when taking Cimetidine? *

What are other drugs people take besides Cimetidine? *

What are other side effects people have besides Osteolysis? *

Joint Pain: 34 people, 89.47%
Injury: 33 people, 86.84%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 32 people, 84.21%
Pain In Extremity: 32 people, 84.21%
Anaemia (lack of blood): 31 people, 81.58%
Bone Density Decreased: 31 people, 81.58%
Nausea And Vomiting: 30 people, 78.95%
Thrombocytopenia (decrease of platelets in blood): 30 people, 78.95%
Neck Pain: 30 people, 78.95%
Osteosclerosis (an elevation in bone density): 29 people, 76.32%

What are the existing conditions these people have? *

Breast Cancer: 22 people, 57.89%
Ovarian Cancer (cancer of ovary): 20 people, 52.63%
Neoplasm Malignant (cancer tumour): 20 people, 52.63%
Migraine (headache): 20 people, 52.63%
Hot Flush (sudden feelings of heat): 20 people, 52.63%
Discomfort: 20 people, 52.63%
Breast Cancer Metastatic: 20 people, 52.63%
Granulocyte Count Decreased: 19 people, 50.00%
Metastases To Bone (cancer spreads to bone): 4 people, 10.53%
Stress And Anxiety: 1 person, 2.63%

* Approximation only. Some reports may have incomplete information.

Do you take Cimetidine and have Osteolysis?

- Check whether Osteolysis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cimetidine:

Cimetidine (10,531 reports)

Osteolysis treatments and more:

Osteolysis (4,092 reports)

Browse all side effects of Cimetidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Osteolysis:

Osteolysis (689 drugs)

Browse all the conditions that are associated with Osteolysis:

Osteolysis (409 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cimetidine (the active ingredients of Cimetidine) and Cimetidine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.