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Cimzia and Multiple sclerosis - a phase IV clinical study of FDA data

Summary:

Multiple sclerosis is reported as a side effect among people who take Cimzia (certolizumab pegol), especially for people who are female, 40-49 old, have been taking the drug for 2 - 5 years also take Cosentyx, and have Psoriatic arthropathy.

The phase IV clinical study analyzes which people have Multiple sclerosis when taking Cimzia. It is created by eHealthMe based on reports of 106,367 people who have side effects when taking Cimzia from the FDA, and is updated regularly.

What is Cimzia?

Cimzia has active ingredients of certolizumab pegol. It is often used in rheumatoid arthritis. eHealthMe is studying from 106,745 Cimzia users. Check the latest studies of Cimzia.

What is Multiple sclerosis?

Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath) is found to be associated with 1,088 drugs and 1,359 conditions by eHealthMe. Check the latest studies of Multiple sclerosis.

On Jul, 20, 2026

106,367 people reported to have side effects when taking Cimzia.
Among them, 52 people (0.05%) have Multiple sclerosis.

Could Cimzia cause Multiple sclerosis?

Among these 52 people:

How long have people been on Cimzia when they have Multiple sclerosis? *

  • < 1 month: 17.65 %
  • 1 - 6 months: 29.41 %
  • 6 - 12 months: 5.88 %
  • 1 - 2 years: 11.76 %
  • 2 - 5 years: 35.29 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Multiple sclerosis when taking Cimzia? *

  • female: 78.72 %
  • male: 21.28 %

What is the age of people who have Multiple sclerosis when taking Cimzia? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 3.33 %
  • 30-39: 16.67 %
  • 40-49: 50.0 %
  • 50-59: 13.33 %
  • 60+: 16.67 %

What are other drugs people take besides Cimzia? *

  1. Arava: 8 people, 15.38%
  2. Cosentyx: 8 people, 15.38%
  3. Otezla: 7 people, 13.46%
  4. Enbrel: 7 people, 13.46%
  5. Humira: 6 people, 11.54%
  6. Vitamin B12: 4 people, 7.69%
  7. Meloxicam: 4 people, 7.69%
  8. Naproxen: 4 people, 7.69%
  9. Humalog: 3 people, 5.77%
  10. Zyrtec: 2 people, 3.85%

What are other side effects people have besides Multiple sclerosis? *

  1. Diarrhea: 10 people, 19.23%
  2. Fatigue (feeling of tiredness): 10 people, 19.23%
  3. Abdominal Discomfort: 8 people, 15.38%
  4. Injection Site Haemorrhage (bleeding from injection site): 8 people, 15.38%
  5. Abdominal Pain Upper: 8 people, 15.38%
  6. Nasopharyngitis (inflammation of the nasopharynx): 8 people, 15.38%
  7. Vessel Puncture Site Bruise: 8 people, 15.38%
  8. Ear Pain: 8 people, 15.38%
  9. Otitis (ear infection): 8 people, 15.38%
  10. Indigestion: 8 people, 15.38%

What are the existing conditions these people have? *

  1. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 17 people, 32.69%
  2. Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 7.69%
  3. Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 7.69%
  4. Uveitis (inflammation of the uvea): 2 people, 3.85%
  5. Pain: 2 people, 3.85%
  6. Neuralgia (pain in one or more nerves): 2 people, 3.85%
  7. Migraine (headache): 2 people, 3.85%
  8. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 3.85%
  9. Parkinson's Disease: 1 person, 1.92%
  10. Osteoporosis (bones weak and more likely to break): 1 person, 1.92%

* Approximation only. Some reports may have incomplete information.

Do you take Cimzia and have Multiple sclerosis?

- Check whether Multiple sclerosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cimzia:

Multiple sclerosis treatments and more:

How severe was Multiple sclerosis and when was it recovered:

Expand to all the drugs that have ingredients of certolizumab pegol:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cimzia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Multiple sclerosis:

Browse all the conditions that are associated with Multiple sclerosis:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on certolizumab pegol (the active ingredients of Cimzia) and Cimzia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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