Cinacalcet hydrochloride and Shunt occlusion - a phase IV clinical study of FDA data

Summary:

Shunt occlusion is reported as a side effect among people who take Cinacalcet hydrochloride (cinacalcet hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Fosrenol, and have Hyperparathyroidism secondary.

The phase IV clinical study analyzes which people have Shunt occlusion when taking Cinacalcet hydrochloride. It is created by eHealthMe based on reports of 2,315 people who have side effects when taking Cinacalcet hydrochloride from the FDA, and is updated regularly.

What is Cinacalcet hydrochloride?

Cinacalcet hydrochloride has active ingredients of cinacalcet hydrochloride. eHealthMe is studying from 2,334 Cinacalcet hydrochloride users. Check the latest studies of Cinacalcet hydrochloride.

What is Shunt occlusion?

Shunt occlusion (blockage of shunt) is found to be associated with 116 drugs and 155 conditions by eHealthMe. Check the latest studies of Shunt occlusion.



On Jul, 11, 2026

2,315 people reported to have side effects when taking Cinacalcet hydrochloride.
Among them, 15 people (0.65%) have Shunt occlusion.

Could Cinacalcet hydrochloride cause Shunt occlusion?

Among these 15 people:

How long have people been on Cinacalcet hydrochloride when they have Shunt occlusion? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 85.71 %
  • 6 - 12 months: 14.29 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Shunt occlusion when taking Cinacalcet hydrochloride? *

  • female: 66.67 %
  • male: 33.33 %

What is the age of people who have Shunt occlusion when taking Cinacalcet hydrochloride? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 6.67 %
  • 60+: 93.33 %

What are other drugs people take besides Cinacalcet hydrochloride? *

  1. Fosrenol: 12 people, 80.00%
  2. Parsabiv: 5 people, 33.33%
  3. Mexiletine Hydrochloride: 3 people, 20.00%
  4. Zetia: 2 people, 13.33%
  5. Calcitriol: 2 people, 13.33%
  6. Evista: 2 people, 13.33%
  7. Lansoprazole: 2 people, 13.33%
  8. Lasix: 2 people, 13.33%
  9. Aspirin: 2 people, 13.33%
  10. Torsemide: 2 people, 13.33%

What are other side effects people have besides Shunt occlusion? *

  1. Shunt Stenosis (narrowing of shunt): 9 people, 60.00%
  2. Cerebral Haemorrhage (bleeding within the brain): 3 people, 20.00%
  3. Arrhythmia Supraventricular (irregular heartbeat supraventricular origin): 3 people, 20.00%
  4. Thrombophlebitis Septic (a condition characterized by venous thrombosis, inflammation, and bacterial infection of blood): 3 people, 20.00%
  5. The Flu (the flu is caused by an influenza virus): 3 people, 20.00%
  6. Sepsis (a severe blood infection that can lead to organ failure and death): 3 people, 20.00%
  7. Salivary Gland Cancer: 3 people, 20.00%
  8. Klebsiella Bacteraemia (klebsiella bacteria in blood after infection to lungs): 3 people, 20.00%
  9. Large Intestine Perforation (hole in large intestine): 3 people, 20.00%
  10. Weight Increased: 3 people, 20.00%

What are the existing conditions these people have? *

  1. Hyperparathyroidism Secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 12 people, 80.00%
  2. Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood): 5 people, 33.33%
  3. Arrhythmia Supraventricular (irregular heartbeat supraventricular origin): 3 people, 20.00%
  4. Nephrogenic Anaemia (anaemia due to kidney disease): 1 person, 6.67%
  5. Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 6.67%
  6. Hyperkalemia (damage to or disease of the kidney): 1 person, 6.67%
  7. Hyperchlorhydria (gastric acid levels are higher in stomach): 1 person, 6.67%
  8. Haemoglobin Increased: 1 person, 6.67%
  9. Gastric Ulcer (stomach ulcer): 1 person, 6.67%
  10. Diabetic Nephropathy (diabetic kidney disease): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Cinacalcet hydrochloride and have Shunt occlusion?

- Check whether Shunt occlusion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cinacalcet hydrochloride:

Shunt occlusion treatments and more:

How severe was Shunt occlusion and when was it recovered:

Expand to all the drugs that have ingredients of cinacalcet hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cinacalcet hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Shunt occlusion:

Browse all the conditions that are associated with Shunt occlusion:


How the study uses the data?

The study uses data from the FDA. It is based on cinacalcet hydrochloride (the active ingredients of Cinacalcet hydrochloride) and Cinacalcet hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: