Citrulline and Dehydration - a phase IV clinical study of FDA data

Summary:

Dehydration is reported as a side effect among people who take Citrulline (l - citrulline), especially for people who are male, 2-9 old, also take Ravicti, and have Amino acid metabolism disorder.

The phase IV clinical study analyzes which people have Dehydration when taking Citrulline. It is created by eHealthMe based on reports of 595 people who have side effects when taking Citrulline from the FDA, and is updated regularly.

What is Citrulline?

Citrulline has active ingredients of l - citrulline. It is often used in erection problems. eHealthMe is studying from 642 Citrulline users. Check the latest studies of Citrulline.

What is Dehydration?

Dehydration (dryness resulting from the removal of water) is found to be associated with 2,753 drugs and 3,349 conditions by eHealthMe. Check the latest studies of Dehydration.



On Jul, 15, 2026

595 people reported to have side effects when taking Citrulline.
Among them, 16 people (2.69%) have Dehydration.

Could Citrulline cause Dehydration?

Among these 16 people:

What is the gender of people who have Dehydration when taking Citrulline? *

  • female: 46.67 %
  • male: 53.33 %

What is the age of people who have Dehydration when taking Citrulline? *

  • 0-1: 21.43 %
  • 2-9: 28.57 %
  • 10-19: 21.43 %
  • 20-29: 14.29 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 14.29 %

What are other drugs people take besides Citrulline? *

  1. Ravicti: 10 people, 62.50%
  2. Valcyte: 2 people, 12.50%
  3. Synthroid: 2 people, 12.50%
  4. Prilosec: 2 people, 12.50%
  5. Prednisone: 2 people, 12.50%
  6. Zantac: 2 people, 12.50%
  7. Vitamin D: 2 people, 12.50%
  8. Miralax: 2 people, 12.50%
  9. Calcium: 2 people, 12.50%
  10. Entresto: 1 person, 6.25%

What are other side effects people have besides Dehydration? *

  1. Nausea And Vomiting: 10 people, 62.50%
  2. Hyperammonaemia: 5 people, 31.25%
  3. Ammonia Increased: 5 people, 31.25%
  4. Abdominal Pain: 4 people, 25.00%
  5. Diarrhea: 4 people, 25.00%
  6. Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 3 people, 18.75%
  7. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 3 people, 18.75%
  8. Nausea (feeling of having an urge to vomit): 3 people, 18.75%
  9. Gastroenteritis (inflammation of stomach and intestine): 2 people, 12.50%
  10. Headache (pain in head): 2 people, 12.50%

What are the existing conditions these people have? *

  1. Amino Acid Metabolism Disorder: 3 people, 18.75%
  2. Carbamoyl Phosphate Synthetase Deficiency (metabolic disorder that causes ammonia to accumulate in the blood): 2 people, 12.50%
  3. Constipation: 2 people, 12.50%
  4. Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 1 person, 6.25%
  5. Asthma: 1 person, 6.25%
  6. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 6.25%
  7. Diabetes: 1 person, 6.25%
  8. Feeling Of Relaxation: 1 person, 6.25%
  9. Gastric Disorder (disease of stomach): 1 person, 6.25%
  10. High Blood Cholesterol: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Citrulline and have Dehydration?

- Check whether Dehydration is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Citrulline:

Dehydration treatments and more:

How severe was Dehydration and when was it recovered:

Expand to all the drugs that have ingredients of l - citrulline:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Citrulline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Dehydration:

Browse all the conditions that are associated with Dehydration:


How the study uses the data?

The study uses data from the FDA. It is based on l - citrulline (the active ingredients of Citrulline) and Citrulline (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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