Clarithromycin and Fluid overload - a phase IV clinical study of FDA data

Summary:

Fluid overload is reported as a side effect among people who take Clarithromycin (clarithromycin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Clotrimazole, and have Pulmonary embolism.

The phase IV clinical study analyzes which people have Fluid overload when taking Clarithromycin. It is created by eHealthMe based on reports of 44,030 people who have side effects when taking Clarithromycin from the FDA, and is updated regularly.

What is Clarithromycin?

Clarithromycin has active ingredients of clarithromycin. It is often used in sinusitis. eHealthMe is studying from 45,044 Clarithromycin users. Check the latest studies of Clarithromycin.

What is Fluid overload?

Fluid overload (too much fluid in the blood) is found to be associated with 1,023 drugs and 1,051 conditions by eHealthMe. Check the latest studies of Fluid overload.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

44,030 people reported to have side effects when taking Clarithromycin.
Among them, 63 people (0.14%) have Fluid overload.

Could Clarithromycin cause Fluid overload?

Among these 63 people:

How long have people been on Clarithromycin when they have Fluid overload? *

What is the gender of people who have Fluid overload when taking Clarithromycin? *

female: 75.86 %
male: 24.14 %

What is the age of people who have Fluid overload when taking Clarithromycin? *

What are other drugs people take besides Clarithromycin? *

What are other side effects people have besides Fluid overload? *

Acute Kidney Failure: 39 people, 61.90%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 35 people, 55.56%
Haemoglobin Decreased: 33 people, 52.38%
Erythema Multiforme (a type of hypersensitivity reaction): 32 people, 50.79%
Oedema Peripheral (superficial swelling): 29 people, 46.03%
Rashes (redness): 26 people, 41.27%
Rash Maculo-Papular (red area on the skin that is covered with small confluent bumps): 25 people, 39.68%
Pain: 25 people, 39.68%
Itching: 25 people, 39.68%
Hypersensitivity: 24 people, 38.10%

What are the existing conditions these people have? *

Pulmonary Embolism (blockage of the main artery of the lung): 27 people, 42.86%
Pain: 5 people, 7.94%
Lower Respiratory Tract Infection: 4 people, 6.35%
Fever: 4 people, 6.35%
High Blood Cholesterol: 4 people, 6.35%
Tuberculosis (a bacterial infection by mycobacterium tuberculosis): 3 people, 4.76%
Multiple Myeloma (cancer of the plasma cells): 3 people, 4.76%
Infective Exacerbation Of Bronchiectasis (severe infective lung disease): 3 people, 4.76%
Nausea (feeling of having an urge to vomit): 3 people, 4.76%
Nausea And Vomiting: 3 people, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Clarithromycin and have Fluid overload?

- Check whether Fluid overload is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Clarithromycin:

Clarithromycin (45,044 reports)

Fluid overload treatments and more:

Fluid overload (20,385 reports)

Browse all side effects of Clarithromycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fluid overload:

Fluid overload (1,023 drugs)

Browse all the conditions that are associated with Fluid overload:

Fluid overload (1,051 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on clarithromycin (the active ingredients of Clarithromycin) and Clarithromycin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.