Clarithromycin and Hypernatraemia - a phase IV clinical study of FDA data

Summary:

Hypernatraemia is reported as a side effect among people who take Clarithromycin (clarithromycin), especially for people who are male, 60+ old, also take Medrol, and have Hepatocellular carcinoma.

The phase IV clinical study analyzes which people have Hypernatraemia when taking Clarithromycin. It is created by eHealthMe based on reports of 44,030 people who have side effects when taking Clarithromycin from the FDA, and is updated regularly.

What is Clarithromycin?

Clarithromycin has active ingredients of clarithromycin. It is often used in sinusitis. eHealthMe is studying from 45,044 Clarithromycin users. Check the latest studies of Clarithromycin.

What is Hypernatraemia?

Hypernatraemia (an abnormally high plasma concentration of sodium ions) is found to be associated with 654 drugs and 805 conditions by eHealthMe. Check the latest studies of Hypernatraemia.

On Jul, 07, 2026

44,030 people reported to have side effects when taking Clarithromycin.
Among them, 20 people (0.05%) have Hypernatraemia.

Could Clarithromycin cause Hypernatraemia?

Among these 20 people:

What is the gender of people who have Hypernatraemia when taking Clarithromycin? *

female: 11.76 %
male: 88.24 %

What is the age of people who have Hypernatraemia when taking Clarithromycin? *

What are other drugs people take besides Clarithromycin? *

What are other side effects people have besides Hypernatraemia? *

Swallowing Pain Or Burning: 5 people, 25.00%
Dehydration (dryness resulting from the removal of water): 4 people, 20.00%
Hypokalemia (low potassium): 4 people, 20.00%
Hyperchloraemia (an excess of chlorides in the blood): 3 people, 15.00%
Cardiac Failure: 2 people, 10.00%
Hospitalisation: 2 people, 10.00%
Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 2 people, 10.00%
Fever: 2 people, 10.00%
Febrile Neutropenia (fever with reduced white blood cells): 2 people, 10.00%
Dizziness: 2 people, 10.00%

What are the existing conditions these people have? *

Hepatocellular Carcinoma (liver cancer): 5 people, 25.00%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 10.00%
Allergic Rhinitis: 2 people, 10.00%
Asthma: 2 people, 10.00%
Lower Respiratory Tract Infection: 2 people, 10.00%
Depression: 1 person, 5.00%
Bipolar Disorder (mood disorder): 1 person, 5.00%
Bladder Irritation: 1 person, 5.00%
Cardiac Failure: 1 person, 5.00%
Constipation: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Clarithromycin and have Hypernatraemia?

- Check whether Hypernatraemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Clarithromycin:

Clarithromycin (45,044 reports)

Hypernatraemia treatments and more:

Hypernatraemia (6,339 reports)

Browse all side effects of Clarithromycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypernatraemia:

Hypernatraemia (654 drugs)

Browse all the conditions that are associated with Hypernatraemia:

Hypernatraemia (805 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on clarithromycin (the active ingredients of Clarithromycin) and Clarithromycin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.