Clarithromycin and Paranasal sinus discomfort - a phase IV clinical study of FDA data

Summary:

Paranasal sinus discomfort is reported as a side effect among people who take Clarithromycin (clarithromycin), especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months also take Vitamin D3, and have Juvenile rheumatoid arthritis.

The phase IV clinical study analyzes which people have Paranasal sinus discomfort when taking Clarithromycin. It is created by eHealthMe based on reports of 44,030 people who have side effects when taking Clarithromycin from the FDA, and is updated regularly.

What is Clarithromycin?

Clarithromycin has active ingredients of clarithromycin. It is often used in sinusitis. eHealthMe is studying from 45,044 Clarithromycin users. Check the latest studies of Clarithromycin.

What is Paranasal sinus discomfort?

Paranasal sinus discomfort is found to be associated with 455 drugs and 398 conditions by eHealthMe. Check the latest studies of Paranasal sinus discomfort.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

44,030 people reported to have side effects when taking Clarithromycin.
Among them, 21 people (0.05%) have Paranasal sinus discomfort.

Could Clarithromycin cause Paranasal sinus discomfort?

Among these 21 people:

How long have people been on Clarithromycin when they have Paranasal sinus discomfort? *

What is the gender of people who have Paranasal sinus discomfort when taking Clarithromycin? *

female: 100 %
male: 0.0 %

What is the age of people who have Paranasal sinus discomfort when taking Clarithromycin? *

What are other drugs people take besides Clarithromycin? *

Prednisone: 9 people, 42.86%
Vitamin D3: 9 people, 42.86%
Cetirizine Hydrochloride: 8 people, 38.10%
Magnesium: 7 people, 33.33%
Calcium Carbonate: 6 people, 28.57%
Risedronate Sodium: 5 people, 23.81%
Colchicine: 5 people, 23.81%
Codeine: 5 people, 23.81%
Clonazepam: 5 people, 23.81%
Clindamycin Hydrochloride: 5 people, 23.81%

What are other side effects people have besides Paranasal sinus discomfort? *

Fever: 14 people, 66.67%
Nausea (feeling of having an urge to vomit): 14 people, 66.67%
Joint Pain: 12 people, 57.14%
Chills (felling of cold): 11 people, 52.38%
Cough: 11 people, 52.38%
Headache (pain in head): 11 people, 52.38%
Rashes (redness): 10 people, 47.62%
Urinary Tract Infection: 10 people, 47.62%
Pain: 10 people, 47.62%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 9 people, 42.86%

What are the existing conditions these people have? *

Urinary Tract Infection: 5 people, 23.81%
Cellulitis (infection under the skin): 5 people, 23.81%
Asthma: 5 people, 23.81%
Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 5 people, 23.81%
Fabry's Disease (build up of a particular type of fat, called globotriaosylceramide, in the body's cells): 3 people, 14.29%
Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 3 people, 14.29%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 14.29%
Trans-Sexualism (an individual identifies with a gender inconsistent or not culturally associated with their assigned sex): 2 people, 9.52%
Stress And Anxiety: 2 people, 9.52%
Respiratory Disorder (respiratory disease): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

Do you take Clarithromycin and have Paranasal sinus discomfort?

- Check whether Paranasal sinus discomfort is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Clarithromycin:

Clarithromycin (45,044 reports)

Browse all side effects of Clarithromycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Paranasal sinus discomfort:

Paranasal sinus discomfort (455 drugs)

Browse all the conditions that are associated with Paranasal sinus discomfort:

Paranasal sinus discomfort (398 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on clarithromycin (the active ingredients of Clarithromycin) and Clarithromycin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.