Claritin and Adrenal insufficiency - a phase IV clinical study of FDA data

Summary:

Adrenal insufficiency is reported as a side effect among people who take Claritin (loratadine), especially for people who are female, 50-59 old, also take Prednisone, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Adrenal insufficiency when taking Claritin. It is created by eHealthMe based on reports of 74,516 people who have side effects when taking Claritin from the FDA, and is updated regularly.

What is Claritin?

Claritin has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 77,316 Claritin users. Check the latest studies of Claritin.

What is Adrenal insufficiency?

Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids) is found to be associated with 965 drugs and 1,094 conditions by eHealthMe. Check the latest studies of Adrenal insufficiency.

On Aug, 13, 2026

74,516 people reported to have side effects when taking Claritin.
Among them, 63 people (0.08%) have Adrenal insufficiency.

Could Claritin cause Adrenal insufficiency?

Among these 63 people:

What is the gender of people who have Adrenal insufficiency when taking Claritin? *

female: 85.19 %
male: 14.81 %

What is the age of people who have Adrenal insufficiency when taking Claritin? *

What are other drugs people take besides Claritin? *

What are other side effects people have besides Adrenal insufficiency? *

Nausea (feeling of having an urge to vomit): 42 people, 66.67%
Depression: 38 people, 60.32%
Pain: 35 people, 55.56%
Back Pain: 32 people, 50.79%
Diarrhea: 31 people, 49.21%
Dizziness: 31 people, 49.21%
Joint Pain: 29 people, 46.03%
Fall: 29 people, 46.03%
Dyspnea (difficult or laboured breathing): 28 people, 44.44%
Fatigue (feeling of tiredness): 27 people, 42.86%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 17 people, 26.98%
Multiple Myeloma (cancer of the plasma cells): 13 people, 20.63%
Hypersensitivity: 12 people, 19.05%
Sleep Disorder: 9 people, 14.29%
Oral Pain: 5 people, 7.94%
Depression: 5 people, 7.94%
Nausea (feeling of having an urge to vomit): 5 people, 7.94%
Oedema (fluid collection in tissue): 5 people, 7.94%
Asthma: 4 people, 6.35%
Tumor Necrosis Factor Receptor-Associated Periodic Syndrome: 4 people, 6.35%

* Approximation only. Some reports may have incomplete information.

Do you take Claritin and have Adrenal insufficiency?

- Check whether Adrenal insufficiency is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Claritin:

Claritin (77,316 reports)

Browse all side effects of Claritin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Adrenal insufficiency:

Adrenal insufficiency (965 drugs)

Browse all the conditions that are associated with Adrenal insufficiency:

Adrenal insufficiency (1,094 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on loratadine (the active ingredients of Claritin) and Claritin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.