Claritin and Aortic valve incompetence - a phase IV clinical study of FDA data

Summary:

Aortic valve incompetence is reported as a side effect among people who take Claritin (loratadine), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Vioxx, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Aortic valve incompetence when taking Claritin. It is created by eHealthMe based on reports of 74,516 people who have side effects when taking Claritin from the FDA, and is updated regularly.

What is Claritin?

Claritin has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 77,317 Claritin users. Check the latest studies of Claritin.

What is Aortic valve incompetence?

Aortic valve incompetence is found to be associated with 910 drugs and 881 conditions by eHealthMe. Check the latest studies of Aortic valve incompetence.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

74,516 people reported to have side effects when taking Claritin.
Among them, 100 people (0.13%) have Aortic valve incompetence.

Could Claritin cause Aortic valve incompetence?

Among these 100 people:

How long have people been on Claritin when they have Aortic valve incompetence? *

What is the gender of people who have Aortic valve incompetence when taking Claritin? *

female: 81.44 %
male: 18.56 %

What is the age of people who have Aortic valve incompetence when taking Claritin? *

What are other drugs people take besides Claritin? *

What are other side effects people have besides Aortic valve incompetence? *

Mitral Valve Incompetence (inefficient heart valve): 74 people, 74.00%
Tricuspid Valve Incompetence (inefficient heart valve): 52 people, 52.00%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 44 people, 44.00%
Dyspnea (difficult or laboured breathing): 40 people, 40.00%
Chest Pain: 38 people, 38.00%
High Blood Pressure: 36 people, 36.00%
Pain: 34 people, 34.00%
Depression: 31 people, 31.00%
Stress And Anxiety: 31 people, 31.00%
Headache (pain in head): 31 people, 31.00%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 12 people, 12.00%
Pain: 10 people, 10.00%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 8.00%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 7 people, 7.00%
High Blood Pressure: 7 people, 7.00%
Osteoporosis (bones weak and more likely to break): 6 people, 6.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 4.00%
Metastases To Bone (cancer spreads to bone): 4 people, 4.00%
Stress And Anxiety: 4 people, 4.00%
Breast Cancer: 4 people, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Claritin and have Aortic valve incompetence?

- Check whether Aortic valve incompetence is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Claritin:

Claritin (77,317 reports)

Browse all side effects of Claritin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Aortic valve incompetence:

Aortic valve incompetence (910 drugs)

Browse all the conditions that are associated with Aortic valve incompetence:

Aortic valve incompetence (881 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on loratadine (the active ingredients of Claritin) and Claritin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.