Claritin and Application site pruritus - a phase IV clinical study of FDA data

Summary:

Application site pruritus is reported as a side effect among people who take Claritin (loratadine), especially for people who are female, 60+ old, also take Daytrana, and have Attention deficit hyperactivity disorder.

The phase IV clinical study analyzes which people have Application site pruritus when taking Claritin. It is created by eHealthMe based on reports of 74,516 people who have side effects when taking Claritin from the FDA, and is updated regularly.

What is Claritin?

Claritin has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 77,317 Claritin users. Check the latest studies of Claritin.

What is Application site pruritus?

Application site pruritus (application site severe itching of the skin) is found to be associated with 537 drugs and 910 conditions by eHealthMe. Check the latest studies of Application site pruritus.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

74,516 people reported to have side effects when taking Claritin.
Among them, 62 people (0.08%) have Application site pruritus.

Could Claritin cause Application site pruritus?

Among these 62 people:

What is the gender of people who have Application site pruritus when taking Claritin? *

female: 73.33 %
male: 26.67 %

What is the age of people who have Application site pruritus when taking Claritin? *

What are other drugs people take besides Claritin? *

Daytrana: 11 people, 17.74%
Benadryl: 6 people, 9.68%
Calcium: 6 people, 9.68%
Neurontin: 5 people, 8.06%
Flolan: 4 people, 6.45%
Flonase: 4 people, 6.45%
Heparin: 4 people, 6.45%
Lasix: 4 people, 6.45%
Cetirizine Hydrochloride: 4 people, 6.45%
Prednisone: 4 people, 6.45%

What are other side effects people have besides Application site pruritus? *

Application Site Erythema (redness of the skin at application site): 39 people, 62.90%
Application Site Irritation: 20 people, 32.26%
Application Site Pain: 16 people, 25.81%
Application Site Rash: 11 people, 17.74%
Itching: 10 people, 16.13%
Rashes (redness): 9 people, 14.52%
Headache (pain in head): 8 people, 12.90%
Diarrhea: 8 people, 12.90%
Urticaria (rash of round, red welts on the skin that itch intensely): 6 people, 9.68%
High Blood Pressure: 6 people, 9.68%

What are the existing conditions these people have? *

Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 11 people, 17.74%
Hypersensitivity: 9 people, 14.52%
Pain: 7 people, 11.29%
Seasonal Allergy (allergic condition due to certain season): 7 people, 11.29%
Depression: 6 people, 9.68%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 8.06%
Bladder Disorder: 4 people, 6.45%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 4 people, 6.45%
High Blood Pressure: 3 people, 4.84%
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 3 people, 4.84%

* Approximation only. Some reports may have incomplete information.

Do you take Claritin and have Application site pruritus?

- Check whether Application site pruritus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Claritin:

Claritin (77,317 reports)

Browse all side effects of Claritin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Application site pruritus:

Application site pruritus (537 drugs)

Browse all the conditions that are associated with Application site pruritus:

Application site pruritus (910 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on loratadine (the active ingredients of Claritin) and Claritin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.