Claritin and Optic atrophy - a phase IV clinical study of FDA data

Summary:

Optic atrophy is reported as a side effect among people who take Claritin (loratadine), especially for people who are male, 60+ old, also take Rebetol, and have Hepatitis c.

The phase IV clinical study analyzes which people have Optic atrophy when taking Claritin. It is created by eHealthMe based on reports of 74,516 people who have side effects when taking Claritin from the FDA, and is updated regularly.

What is Claritin?

Claritin has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 77,315 Claritin users. Check the latest studies of Claritin.

What is Optic atrophy?

Optic atrophy (the loss of a proportion of optic disc nerve fibres) is found to be associated with 249 drugs and 453 conditions by eHealthMe. Check the latest studies of Optic atrophy.



On Jul, 15, 2026

74,516 people reported to have side effects when taking Claritin.
Among them, 17 people (0.02%) have Optic atrophy.

Could Claritin cause Optic atrophy?

Among these 17 people:

What is the gender of people who have Optic atrophy when taking Claritin? *

  • female: 23.53 %
  • male: 76.47 %

What is the age of people who have Optic atrophy when taking Claritin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 17.65 %
  • 50-59: 41.18 %
  • 60+: 41.18 %

What are other drugs people take besides Claritin? *

  1. Peg-Intron: 11 people, 64.71%
  2. Rebetol: 11 people, 64.71%
  3. Serevent: 10 people, 58.82%
  4. Klonopin: 10 people, 58.82%
  5. Buspar: 10 people, 58.82%
  6. Flovent: 9 people, 52.94%
  7. Flonase: 9 people, 52.94%
  8. Flomax: 7 people, 41.18%
  9. Zoloft: 7 people, 41.18%
  10. Remeron: 6 people, 35.29%

What are other side effects people have besides Optic atrophy? *

  1. Stress And Anxiety: 12 people, 70.59%
  2. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 12 people, 70.59%
  3. Blindness: 11 people, 64.71%
  4. Optic Neuritis (optic nerve inflammation): 11 people, 64.71%
  5. Papilloedema (optic disc swelling): 11 people, 64.71%
  6. Weight Decreased: 10 people, 58.82%
  7. Fainting (loss of consciousness and postural tone): 10 people, 58.82%
  8. Arrhythmias (irregular heartbeat): 9 people, 52.94%
  9. Keratitis (eye's cornea, the front part of the eye, becomes inflamed): 9 people, 52.94%
  10. Macular Degeneration (painless eye condition that leads to the gradual loss of central vision): 8 people, 47.06%

What are the existing conditions these people have? *

  1. Hepatitis C: 11 people, 64.71%
  2. Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 11.76%
  3. High Blood Cholesterol: 2 people, 11.76%
  4. Growth Hormone Deficiency: 2 people, 11.76%
  5. Erection Problems: 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

Do you take Claritin and have Optic atrophy?

- Check whether Optic atrophy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Claritin:

Optic atrophy treatments and more:

How severe was Optic atrophy and when was it recovered:

Expand to all the drugs that have ingredients of loratadine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Claritin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Optic atrophy:

Browse all the conditions that are associated with Optic atrophy:


How the study uses the data?

The study uses data from the FDA. It is based on loratadine (the active ingredients of Claritin) and Claritin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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