Cleocin and Aphthous stomatitis - a phase IV clinical study of FDA data

Summary:

Aphthous stomatitis is reported as a side effect among people who take Cleocin (clindamycin phosphate), especially for people who are female, 30-39 old, also take Accutane, and have Acne cystic.

The phase IV clinical study analyzes which people have Aphthous stomatitis when taking Cleocin. It is created by eHealthMe based on reports of 3,734 people who have side effects when taking Cleocin from the FDA, and is updated regularly.

What is Cleocin?

Cleocin has active ingredients of clindamycin phosphate. It is often used in infection. eHealthMe is studying from 3,940 Cleocin users. Check the latest studies of Cleocin.

What is Aphthous stomatitis?

Aphthous stomatitis (mouth ulcer) is found to be associated with 428 drugs and 811 conditions by eHealthMe. Check the latest studies of Aphthous stomatitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

3,734 people reported to have side effects when taking Cleocin.
Among them, 12 people (0.32%) have Aphthous stomatitis.

Could Cleocin cause Aphthous stomatitis?

Among these 12 people:

What is the gender of people who have Aphthous stomatitis when taking Cleocin? *

female: 66.67 %
male: 33.33 %

What is the age of people who have Aphthous stomatitis when taking Cleocin? *

What are other drugs people take besides Cleocin? *

What are other side effects people have besides Aphthous stomatitis? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 10 people, 83.33%
Anaemia (lack of blood): 10 people, 83.33%
Inflammatory Bowel Disease: 10 people, 83.33%
Multi-Organ Disorder (multiple organ disease): 9 people, 75.00%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 9 people, 75.00%
Chest Pain: 9 people, 75.00%
Joint Pain: 9 people, 75.00%
Weight Decreased: 8 people, 66.67%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 8 people, 66.67%
Intestinal Haemorrhage (bleeding from intestine): 7 people, 58.33%

What are the existing conditions these people have? *

Acne Cystic (skin problems that cause pimples): 3 people, 25.00%
Sinusitis (inflammation of sinus): 2 people, 16.67%
Pain: 2 people, 16.67%
Gastric Ulcer (stomach ulcer): 2 people, 16.67%
Allergic Sinusitis: 2 people, 16.67%
Weakness: 1 person, 8.33%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 8.33%
Muscle Disorder (muscle disease): 1 person, 8.33%
Metastases To Bone (cancer spreads to bone): 1 person, 8.33%
Hiv Infection: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Cleocin and have Aphthous stomatitis?

- Check whether Aphthous stomatitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cleocin:

Cleocin (3,940 reports)

Browse all side effects of Cleocin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Aphthous stomatitis:

Aphthous stomatitis (428 drugs)

Browse all the conditions that are associated with Aphthous stomatitis:

Aphthous stomatitis (811 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on clindamycin phosphate (the active ingredients of Cleocin) and Cleocin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.