Clolar and Constipation - a phase IV clinical study of FDA data
Summary:
Constipation is reported as a side effect among people who take Clolar (clofarabine), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Ondansetron, and have Acute leukaemia.
The phase IV clinical study analyzes which people have Constipation when taking Clolar. It is created by eHealthMe based on reports of 1,091 people who have side effects when taking Clolar from the FDA, and is updated regularly.
What is Clolar?
Clolar has active ingredients of clofarabine. eHealthMe is studying from 1,093 Clolar users. Check the latest studies of Clolar.
What is Constipation?
Constipation is found to be associated with 3,004 drugs and 4,619 conditions by eHealthMe. Check the latest studies of Constipation.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
1,091 people reported to have side effects when taking Clolar.
Among them, 17 people (1.56%) have Constipation.

Among these 17 people:
How long have people been on Clolar when they have Constipation? *
- < 1 month: 93.33 %
- 1 - 6 months: 6.67 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Constipation when taking Clolar? *
- female: 47.06 %
- male: 52.94 %
What is the age of people who have Constipation when taking Clolar? *
- 0-1: 0.0 %
- 2-9: 12.5 %
- 10-19: 12.5 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 0.0 %
- 50-59: 12.5 %
- 60+: 62.5 %
What are other drugs people take besides Clolar? *
- Ondansetron: 7 people, 41.18%
- Hydrocortisone: 3 people, 17.65%
- Acetaminophen: 3 people, 17.65%
- Allopurinol: 3 people, 17.65%
- Fluconazole: 3 people, 17.65%
- Cyclophosphamide: 3 people, 17.65%
- Vancomycin: 2 people, 11.76%
- Bactrim: 2 people, 11.76%
- Oxycodone: 2 people, 11.76%
- Dexamethasone: 1 person, 5.88%
What are other side effects people have besides Constipation? *
- Febrile Neutropenia (fever with reduced white blood cells): 11 people, 64.71%
- Haemoglobin Decreased: 7 people, 41.18%
- Urinary Retention (the inability to completely or partially empty the bladder): 6 people, 35.29%
- Fatigue (feeling of tiredness): 5 people, 29.41%
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 4 people, 23.53%
- Hallucinations (sensations that appear real but are created by your mind): 4 people, 23.53%
- Dyspnea (difficult or laboured breathing): 3 people, 17.65%
- Heart Attack: 3 people, 17.65%
- Insomnia (sleeplessness): 3 people, 17.65%
- Delusion (a false belief or opinion): 3 people, 17.65%
What are the existing conditions these people have? *
- Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 6 people, 35.29%
- Acute Leukaemia (blood cancer): 6 people, 35.29%
- B-Cell Type Acute Leukaemia (cancer of the white blood cells): 2 people, 11.76%
- Nausea (feeling of having an urge to vomit): 1 person, 5.88%
- Mantle Cell Lymphoma Recurrent (cancer of lymphocytes, a type of white blood cell- recurrent): 1 person, 5.88%
- Lymphocytic Leukaemia (a type of cancer in which the bone marrow makes too many lymphocytes): 1 person, 5.88%
- Hypophagia (reduced food intake): 1 person, 5.88%
- Diarrhea: 1 person, 5.88%
- Cancer Pain: 1 person, 5.88%
- Bone Marrow Conditioning Regimen: 1 person, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Clolar and have Constipation?
- Check whether Constipation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Clolar:
- Clolar (1,093 reports)
Constipation treatments and more:
- Constipation (337,881 reports)
How severe was Constipation and when was it recovered:
Expand to all the drugs that have ingredients of clofarabine:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Clolar:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Constipation:
- Constipation (3,004 drugs)
Browse all the conditions that are associated with Constipation:
- Constipation (4,619 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on clofarabine (the active ingredients of Clolar) and Clolar (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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