Clolar and Hyponatremia - a phase IV clinical study of FDA data

Summary:

Hyponatremia is reported as a side effect among people who take Clolar (clofarabine), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Cytarabine, and have Acute myeloid leukaemia.

The phase IV clinical study analyzes which people have Hyponatremia when taking Clolar. It is created by eHealthMe based on reports of 1,091 people who have side effects when taking Clolar from the FDA, and is updated regularly.

What is Clolar?

Clolar has active ingredients of clofarabine. eHealthMe is studying from 1,093 Clolar users. Check the latest studies of Clolar.

What is Hyponatremia?

Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration) is found to be associated with 1,940 drugs and 2,272 conditions by eHealthMe. Check the latest studies of Hyponatremia.

On Jul, 31, 2026

1,091 people reported to have side effects when taking Clolar.
Among them, 12 people (1.1%) have Hyponatremia.

Among these 12 people:

How long have people been on Clolar when they have Hyponatremia? *

What is the gender of people who have Hyponatremia when taking Clolar? *

female: 83.33 %
male: 16.67 %

What is the age of people who have Hyponatremia when taking Clolar? *

What are other drugs people take besides Clolar? *

What are other side effects people have besides Hyponatremia? *

Hypokalemia (low potassium): 7 people, 58.33%
Diarrhea: 5 people, 41.67%
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low): 5 people, 41.67%
Abdominal Pain: 4 people, 33.33%
Thrombocytopenia (decrease of platelets in blood): 4 people, 33.33%
Dyspnea (difficult or laboured breathing): 4 people, 33.33%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 3 people, 25.00%
Neutropenic Infection (infection with less neutrophil numbers in blood): 3 people, 25.00%
Nodal Arrhythmia (an irregular heart beat originating from within the atrioventricular node): 3 people, 25.00%
Oedema Peripheral (superficial swelling): 3 people, 25.00%

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 4 people, 33.33%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 3 people, 25.00%
Lymphocytic Leukaemia (a type of cancer in which the bone marrow makes too many lymphocytes): 2 people, 16.67%
Thyroid Diseases: 1 person, 8.33%
Sepsis (a severe blood infection that can lead to organ failure and death): 1 person, 8.33%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 1 person, 8.33%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 1 person, 8.33%
Angioimmunoblastic T-Cell Lymphoma Recurrent (mature t-cell cancer of the blood or lymph vessel-recurrent): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Clolar and have Hyponatremia?

- Check whether Hyponatremia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Clolar:

Clolar (1,093 reports)

Hyponatremia treatments and more:

Hyponatremia (72,436 reports)

Browse all side effects of Clolar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyponatremia:

Hyponatremia (1,940 drugs)

Browse all the conditions that are associated with Hyponatremia:

Hyponatremia (2,272 conditions)

Related publications that referenced our studies

Choi N, Lee JY, Sunwoo JS, Kwon KI, Roh H, Ahn MY, Lee KB, "Hyponatremia during Acyclovir Treatment of Bell’s Palsy", Journal of the Korean Neurological Association, 2017 Aug .
Koza Y, Ta? MH, ?im?ek Z, Gündo?du F, "Hyponatremia and heart failure: the overlooked piece of the puzzle", Anatolian journal of cardiology, 2016 Jan .
Das S, Bandyopadhyay S, Ramasamy A, Prabhu VV, Pachiappan S, "A case of losartan-induced severe hyponatremia", Journal of pharmacology & pharmacotherapeutics, 2015 Jan .
Gupta E, Kunjal R, Cury JD, "Severe hyponatremia due to valproic acid toxicity", Journal of clinical medicine research, 2015 Jan .
Kate N, Grover S, Kumar S, Modi M, "Bupropion-induced hyponatremia", General hospital psychiatry, 2013 Dec .
Choi N, Lee JY, Sunwoo JS, Kwon KI, Roh H, Ahn MY, Lee KB, "Hyponatremia during Acyclovir Treatment of Bell’s Palsy", Journal of the Korean Neurological Association, 2017 Aug .
Koza Y, Ta? MH, ?im?ek Z, Gündo?du F, "Hyponatremia and heart failure: the overlooked piece of the puzzle", Anatolian journal of cardiology, 2016 Jan .
Das S, Bandyopadhyay S, Ramasamy A, Prabhu VV, Pachiappan S, "A case of losartan-induced severe hyponatremia", Journal of pharmacology & pharmacotherapeutics, 2015 Jan .
Gupta E, Kunjal R, Cury JD, "Severe hyponatremia due to valproic acid toxicity", Journal of clinical medicine research, 2015 Jan .
Kate N, Grover S, Kumar S, Modi M, "Bupropion-induced hyponatremia", General hospital psychiatry, 2013 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on clofarabine (the active ingredients of Clolar) and Clolar (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.