Clonidine hydrochloride and Adverse drug reaction - a phase IV clinical study of FDA data

Summary:

Adverse drug reaction is reported as a side effect among people who take Clonidine hydrochloride (clonidine hydrochloride), especially for people who are female, 50-59 old, also take Acetaminophen, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Adverse drug reaction when taking Clonidine hydrochloride. It is created by eHealthMe based on reports of 4,628 people who have side effects when taking Clonidine hydrochloride from the FDA, and is updated regularly.

What is Clonidine hydrochloride?

Clonidine hydrochloride has active ingredients of clonidine hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 5,643 Clonidine hydrochloride users. Check the latest studies of Clonidine hydrochloride.

What is Adverse drug reaction?

Adverse drug reaction is found to be associated with 1,631 drugs and 1,551 conditions by eHealthMe. Check the latest studies of Adverse drug reaction.

On Jul, 06, 2026

4,628 people reported to have side effects when taking Clonidine hydrochloride.
Among them, 56 people (1.21%) have Adverse drug reaction.

Could Clonidine hydrochloride cause Adverse drug reaction?

Among these 56 people:

What is the gender of people who have Adverse drug reaction when taking Clonidine hydrochloride? *

female: 74.47 %
male: 25.53 %

What is the age of people who have Adverse drug reaction when taking Clonidine hydrochloride? *

What are other drugs people take besides Clonidine hydrochloride? *

Acetaminophen: 34 people, 60.71%
Prednisone: 32 people, 57.14%
Remicade: 32 people, 57.14%
Simponi: 31 people, 55.36%
Asacol: 31 people, 55.36%
Bupivacaine Hydrochloride: 31 people, 55.36%
Calcium Carbonate: 31 people, 55.36%
Cetirizine Hydrochloride: 31 people, 55.36%
Cimzia: 31 people, 55.36%
Folic Acid: 31 people, 55.36%

What are other side effects people have besides Adverse drug reaction? *

Fatigue (feeling of tiredness): 36 people, 64.29%
Nausea And Vomiting: 31 people, 55.36%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 31 people, 55.36%
C-Reactive Protein Increased: 31 people, 55.36%
Dizziness: 31 people, 55.36%
High Blood Cholesterol: 31 people, 55.36%
Adverse Event: 30 people, 53.57%
Headache (pain in head): 30 people, 53.57%
Infusion Related Reaction: 29 people, 51.79%
Hypoaesthesia (reduced sense of touch or sensation): 29 people, 51.79%

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 31 people, 55.36%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 31 people, 55.36%
Indigestion: 28 people, 50.00%
Psoriasis (immune-mediated disease that affects the skin): 19 people, 33.93%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 11 people, 19.64%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 10 people, 17.86%
Fibromyalgia (a long-term condition which causes pain all over the body): 10 people, 17.86%
Headache (pain in head): 8 people, 14.29%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 5 people, 8.93%
Pain: 4 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Clonidine hydrochloride and have Adverse drug reaction?

- Check whether Adverse drug reaction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Clonidine hydrochloride:

Clonidine hydrochloride (5,643 reports)

Browse all side effects of Clonidine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Adverse drug reaction:

Adverse drug reaction (1,631 drugs)

Browse all the conditions that are associated with Adverse drug reaction:

Adverse drug reaction (1,551 conditions)

Related publications that referenced our studies

Dong H, Zhang J, Ren L, Liu Q, Zhu S, "Unexpected death due to cefuroxime-induced disulfiram-like reaction", Indian journal of pharmacology, 2013 Jan .
Dong H, Zhang J, Ren L, Liu Q, Zhu S, "Unexpected death due to cefuroxime-induced disulfiram-like reaction", Indian journal of pharmacology, 2013 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on clonidine hydrochloride (the active ingredients of Clonidine hydrochloride) and Clonidine hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.