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Clozapine and Psoriasis - a phase IV clinical study of FDA data

Summary:

Psoriasis is reported as a side effect among people who take Clozapine (clozapine), especially for people who are male, 40-49 old, have been taking the drug for 1 - 6 months also take Fluoxetine, and have Bipolar disorder.

The phase IV clinical study analyzes which people have Psoriasis when taking Clozapine. It is created by eHealthMe based on reports of 83,401 people who have side effects when taking Clozapine from the FDA, and is updated regularly.

What is Clozapine?

Clozapine has active ingredients of clozapine. It is often used in schizophrenia. eHealthMe is studying from 83,728 Clozapine users. Check the latest studies of Clozapine.

What is Psoriasis?

Psoriasis (immune-mediated disease that affects the skin) is found to be associated with 1,476 drugs and 1,694 conditions by eHealthMe. Check the latest studies of Psoriasis.

On Jul, 21, 2026

83,401 people reported to have side effects when taking Clozapine.
Among them, 46 people (0.06%) have Psoriasis.

Could Clozapine cause Psoriasis?

Among these 46 people:

How long have people been on Clozapine when they have Psoriasis? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Psoriasis when taking Clozapine? *

  • female: 48.84 %
  • male: 51.16 %

What is the age of people who have Psoriasis when taking Clozapine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 14.29 %
  • 30-39: 21.43 %
  • 40-49: 39.29 %
  • 50-59: 10.71 %
  • 60+: 14.29 %

What are other drugs people take besides Clozapine? *

  1. Fluoxetine: 13 people, 28.26%
  2. Lamotrigine: 10 people, 21.74%
  3. Diazepam: 9 people, 19.57%
  4. Clonazepam: 8 people, 17.39%
  5. Olanzapine: 8 people, 17.39%
  6. Valproic Acid: 7 people, 15.22%
  7. Zopiclone: 6 people, 13.04%
  8. Humira: 4 people, 8.70%
  9. Tecfidera: 4 people, 8.70%
  10. Skyrizi: 4 people, 8.70%

What are other side effects people have besides Psoriasis? *

  1. Joint Pain: 9 people, 19.57%
  2. Nephropathy (damage to or disease of a kidney): 8 people, 17.39%
  3. Parkinson's Disease: 8 people, 17.39%
  4. Pleurothotonus (neurological disorder which occurs due to prolonged exposure to antipsychotic drugs): 8 people, 17.39%
  5. Rashes (redness): 6 people, 13.04%
  6. Fall: 6 people, 13.04%
  7. Weakness: 6 people, 13.04%
  8. Depression: 5 people, 10.87%
  9. Memory Loss: 5 people, 10.87%
  10. Metabolic Syndrome (a combination of the medical disorders that, when occurring together, increase the risk of developing cardiovascular disease): 5 people, 10.87%

What are the existing conditions these people have? *

  1. Bipolar Disorder (mood disorder): 10 people, 21.74%
  2. Mania (a state of abnormally elevated or irritable mood): 8 people, 17.39%
  3. Psychotic Disorder: 5 people, 10.87%
  4. Depression: 5 people, 10.87%
  5. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 10.87%
  6. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 5 people, 10.87%
  7. Affective Disorder (mental disorder): 4 people, 8.70%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 6.52%
  9. Sinus Tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 3 people, 6.52%
  10. Asthma: 2 people, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Clozapine and have Psoriasis?

- Check whether Psoriasis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Clozapine:

Psoriasis treatments and more:

How severe was Psoriasis and when was it recovered:

Expand to all the drugs that have ingredients of clozapine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Clozapine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Psoriasis:

Browse all the conditions that are associated with Psoriasis:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on clozapine (the active ingredients of Clozapine) and Clozapine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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