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Clozapine and Sleep walking - a phase IV clinical study of FDA data

Summary:

Sleep walking is reported as a side effect among people who take Clozapine (clozapine), especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years also take Clonazepam, and have Extrapyramidal disorder.

The phase IV clinical study analyzes which people have Sleep walking when taking Clozapine. It is created by eHealthMe based on reports of 83,401 people who have side effects when taking Clozapine from the FDA, and is updated regularly.

What is Clozapine?

Clozapine has active ingredients of clozapine. It is often used in schizophrenia. eHealthMe is studying from 83,728 Clozapine users. Check the latest studies of Clozapine.

What is Sleep walking?

Sleep walking (walking during sleep) is found to be associated with 678 drugs and 1,124 conditions by eHealthMe. Check the latest studies of Sleep walking.

On Jul, 25, 2026

83,401 people reported to have side effects when taking Clozapine.
Among them, 19 people (0.02%) have Sleep walking.

Could Clozapine cause Sleep walking?

Among these 19 people:

How long have people been on Clozapine when they have Sleep walking? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 50 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 50 %
  • 10+ years: 0.0 %

What is the gender of people who have Sleep walking when taking Clozapine? *

  • female: 83.33 %
  • male: 16.67 %

What is the age of people who have Sleep walking when taking Clozapine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 23.08 %
  • 40-49: 15.38 %
  • 50-59: 61.54 %
  • 60+: 0.0 %

What are other drugs people take besides Clozapine? *

  1. Clonazepam: 8 people, 42.11%
  2. Clozaril: 6 people, 31.58%
  3. Phenytoin: 4 people, 21.05%
  4. Diazepam: 4 people, 21.05%
  5. Sertraline Hydrochloride: 3 people, 15.79%
  6. Quetiapine Fumarate: 2 people, 10.53%
  7. Hydromorphone Hydrochloride: 2 people, 10.53%
  8. Xyrem: 2 people, 10.53%
  9. Boniva: 2 people, 10.53%
  10. Sertraline: 2 people, 10.53%

What are other side effects people have besides Sleep walking? *

  1. Hypotension (abnormally low blood pressure): 9 people, 47.37%
  2. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 8 people, 42.11%
  3. Akathisia (a movement disorder characterized by a feeling of inner restlessness): 8 people, 42.11%
  4. Movement - Uncontrolled Or Slow: 8 people, 42.11%
  5. Temporomandibular Joint Syndrome (pain at the temporomandibular joint due to various causes of increased muscle tension and spasm. it is believed that syndrome is a physical manifestation of psychological stress): 8 people, 42.11%
  6. Speech Disorder: 8 people, 42.11%
  7. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 8 people, 42.11%
  8. Tardive Dyskinesia (a disorder that involves involuntary movements): 7 people, 36.84%
  9. Pain: 7 people, 36.84%
  10. Pain In Jaw: 6 people, 31.58%

What are the existing conditions these people have? *

  1. Stress And Anxiety: 4 people, 21.05%
  2. Joint Pain: 4 people, 21.05%
  3. Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 4 people, 21.05%
  4. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 10.53%
  5. Depression: 2 people, 10.53%
  6. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 10.53%
  7. Akathisia (a movement disorder characterized by a feeling of inner restlessness): 2 people, 10.53%
  8. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 1 person, 5.26%
  9. Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 1 person, 5.26%
  10. Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Clozapine and have Sleep walking?

- Check whether Sleep walking is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Clozapine:

Sleep walking treatments and more:

How severe was Sleep walking and when was it recovered:

Expand to all the drugs that have ingredients of clozapine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Clozapine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sleep walking:

Browse all the conditions that are associated with Sleep walking:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on clozapine (the active ingredients of Clozapine) and Clozapine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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