Clozapine and Testis cancer - a phase IV clinical study of FDA data

Summary:

Testis cancer is reported as a side effect among people who take Clozapine (clozapine), especially for people who are 20-29 old, have been taking the drug for 5 - 10 years also take Risperidone, and have Borderline personality disorder.

The phase IV clinical study analyzes which people have Testis cancer when taking Clozapine. It is created by eHealthMe based on reports of 83,401 people who have side effects when taking Clozapine from the FDA, and is updated regularly.

What is Clozapine?

Clozapine has active ingredients of clozapine. It is often used in schizophrenia. eHealthMe is studying from 83,728 Clozapine users. Check the latest studies of Clozapine.

What is Testis cancer?

Testis cancer (testes cancer) is found to be associated with 73 drugs and 245 conditions by eHealthMe. Check the latest studies of Testis cancer.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 27, 2026

83,401 people reported to have side effects when taking Clozapine.
Among them, 12 people (0.01%) have Testis cancer.

Could Clozapine cause Testis cancer?

Among these 12 people:

How long have people been on Clozapine when they have Testis cancer? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 25 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 75 %
  • 10+ years: 0.0 %

What is the age of people who have Testis cancer when taking Clozapine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 42.86 %
  • 20-29: 42.86 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 14.29 %

What are other drugs people take besides Clozapine? *

  1. Risperidone: 3 people, 25.00%
  2. Clonazepam: 2 people, 16.67%
  3. Zoloft: 1 person, 8.33%
  4. Mirabegron: 1 person, 8.33%
  5. Aspirin: 1 person, 8.33%
  6. Ativan: 1 person, 8.33%
  7. Carbatrol: 1 person, 8.33%
  8. Famotidine: 1 person, 8.33%
  9. Ibuprofen: 1 person, 8.33%
  10. Midodrine Hydrochloride: 1 person, 8.33%

What are other side effects people have besides Testis cancer? *

  1. Salivary Hypersecretion (excess saliva secretion): 3 people, 25.00%
  2. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 16.67%
  3. Weight Increased: 1 person, 8.33%
  4. Hallucination, Visual (seeing things that aren't there): 1 person, 8.33%
  5. Hallucination, Tactile (sensation of physical contact with an object that isn't there): 1 person, 8.33%
  6. Gaze Palsy (disorders affecting the ability to move both eyes in the same direction): 1 person, 8.33%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 8.33%
  8. Fever: 1 person, 8.33%
  9. Fatigue (feeling of tiredness): 1 person, 8.33%
  10. Fall: 1 person, 8.33%

What are the existing conditions these people have? *

  1. Borderline Personality Disorder: 3 people, 25.00%
  2. Insomnia (sleeplessness): 2 people, 16.67%
  3. Parkinson's Disease: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Clozapine and have Testis cancer?

- Check whether Testis cancer is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Clozapine:

Testis cancer treatments and more:

How severe was Testis cancer and when was it recovered:

Expand to all the drugs that have ingredients of clozapine:

Sub-studies by age:

0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Clozapine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Testis cancer:

Browse all the conditions that are associated with Testis cancer:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on clozapine (the active ingredients of Clozapine) and Clozapine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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