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Clozaril and Drop attacks - a phase IV clinical study of FDA data

Summary:

Drop attacks is reported as a side effect among people who take Clozaril (clozapine), especially for people who are male, 20-29 old, have been taking the drug for 2 - 5 years also take Valproate Sodium, and have Schizophrenia, residual type.

The phase IV clinical study analyzes which people have Drop attacks when taking Clozaril. It is created by eHealthMe based on reports of 64,938 people who have side effects when taking Clozaril from the FDA, and is updated regularly.

What is Clozaril?

Clozaril has active ingredients of clozapine. It is often used in schizophrenia. eHealthMe is studying from 65,127 Clozaril users. Check the latest studies of Clozaril.

What is Drop attacks?

Drop attacks (sudden spontaneous falls while standing or walking) is found to be associated with 146 drugs and 237 conditions by eHealthMe. Check the latest studies of Drop attacks.

On Aug, 07, 2026

64,938 people reported to have side effects when taking Clozaril.
Among them, 32 people (0.05%) have Drop attacks.

Could Clozaril cause Drop attacks?

Among these 32 people:

How long have people been on Clozaril when they have Drop attacks? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 18.18 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 72.73 %
  • 5 - 10 years: 9.09 %
  • 10+ years: 0.0 %

What is the gender of people who have Drop attacks when taking Clozaril? *

  • female: 40.62 %
  • male: 59.38 %

What is the age of people who have Drop attacks when taking Clozaril? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 3.45 %
  • 20-29: 41.38 %
  • 30-39: 27.59 %
  • 40-49: 10.34 %
  • 50-59: 13.79 %
  • 60+: 3.45 %

What are other drugs people take besides Clozaril? *

  1. Valproate Sodium: 7 people, 21.88%
  2. Clopidogrel: 5 people, 15.62%
  3. Aripiprazole: 5 people, 15.62%
  4. Bumetanide: 5 people, 15.62%
  5. Ramipril: 5 people, 15.62%
  6. Metolazone: 5 people, 15.62%
  7. Aspirin: 4 people, 12.50%
  8. Metoprolol Tartrate: 4 people, 12.50%
  9. Haloperidol: 4 people, 12.50%
  10. Omeprazole: 3 people, 9.38%

What are other side effects people have besides Drop attacks? *

  1. Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles): 18 people, 56.25%
  2. Weakness: 9 people, 28.12%
  3. Fall: 8 people, 25.00%
  4. Loss Of Consciousness: 8 people, 25.00%
  5. Oedema Peripheral (superficial swelling): 6 people, 18.75%
  6. Arrhythmias (irregular heartbeat): 6 people, 18.75%
  7. Cardiac Disorder: 6 people, 18.75%
  8. Cardiac Failure: 6 people, 18.75%
  9. Circulatory Collapse: 6 people, 18.75%
  10. Conduction Disorder (serious disorder of the heart not responses proper to impulses): 6 people, 18.75%

What are the existing conditions these people have? *

  1. Schizophrenia, Residual Type (a condition manifested by individuals with symptoms of schizophrenia who, after a psychotic schizophrenic episode, are no longer psychotic): 4 people, 12.50%
  2. Salivary Hypersecretion (excess saliva secretion): 3 people, 9.38%
  3. Myoclonic Epilepsy (type of epilepsy with quick little jerks of the arms, shoulder, or occasionally the legs): 3 people, 9.38%
  4. Depression: 2 people, 6.25%
  5. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 6.25%
  6. Schizophrenia, Paranoid Type (delusions and auditory hallucinations but relatively normal intellectual functioning and expression of affect): 1 person, 3.12%
  7. Reflux Gastritis (a condition in which the lining of a person's stomach becomes inflamed as a result of exposure to bile): 1 person, 3.12%
  8. Psychotic Disorder: 1 person, 3.12%
  9. Indigestion: 1 person, 3.12%
  10. Gastrointestinal Discomfort: 1 person, 3.12%

* Approximation only. Some reports may have incomplete information.

Do you take Clozaril and have Drop attacks?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Clozaril:

Drop attacks treatments and more:

How severe was Drop attacks and when was it recovered:

Expand to all the drugs that have ingredients of clozapine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Clozaril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Drop attacks:

Browse all the conditions that are associated with Drop attacks:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on clozapine (the active ingredients of Clozaril) and Clozaril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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