Co-codamol and Urinary retention - a phase IV clinical study of FDA data

Summary:

Urinary retention is reported as a side effect among people who take Co-codamol (acetaminophen; codeine phosphate), especially for people who are male, 50-59 old, also take Baclofen, and have Constipation.

The phase IV clinical study analyzes which people have Urinary retention when taking Co-codamol. It is created by eHealthMe based on reports of 1,873 people who have side effects when taking Co-codamol from the FDA, and is updated regularly.

What is Co-codamol?

Co-codamol has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 2,364 Co-codamol users. Check the latest studies of Co-codamol.

What is Urinary retention?

Urinary retention (the inability to completely or partially empty the bladder) is found to be associated with 1,572 drugs and 1,735 conditions by eHealthMe. Check the latest studies of Urinary retention.

On Apr, 22, 2026

1,873 people reported to have side effects when taking Co-codamol.
Among them, 13 people (0.69%) have Urinary retention.

Could Co-codamol cause Urinary retention?

Among these 13 people:

What is the gender of people who have Urinary retention when taking Co-codamol? *

female: 15.38 %
male: 84.62 %

What is the age of people who have Urinary retention when taking Co-codamol? *

What are other drugs people take besides Co-codamol? *

Baclofen: 5 people, 38.46%
Tapentadol Hydrochloride: 4 people, 30.77%
Tramadol: 3 people, 23.08%
Senna: 2 people, 15.38%
Paracetamol: 2 people, 15.38%
Clozaril: 2 people, 15.38%
Valproate Sodium: 2 people, 15.38%
Movicol: 2 people, 15.38%
Lorazepam: 2 people, 15.38%
Hydrocortisone: 1 person, 7.69%

What are other side effects people have besides Urinary retention? *

Malaise (a feeling of general discomfort or uneasiness): 8 people, 61.54%
Headache (pain in head): 8 people, 61.54%
High Blood Pressure: 7 people, 53.85%
Stress And Anxiety: 7 people, 53.85%
Insomnia (sleeplessness): 6 people, 46.15%
Drug Ineffective: 6 people, 46.15%
Constipation: 4 people, 30.77%
Dizziness: 3 people, 23.08%
Agitation (state of anxiety or nervous excitement): 3 people, 23.08%
Dyspnea (difficult or laboured breathing): 3 people, 23.08%

What are the existing conditions these people have? *

Constipation: 3 people, 23.08%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 15.38%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 7.69%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 7.69%
Asthma: 1 person, 7.69%
Breakthrough Pain: 1 person, 7.69%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 7.69%
Depression: 1 person, 7.69%
Diaphragmalgia (pain in the diaphragm): 1 person, 7.69%
Diarrhea: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Co-codamol and have Urinary retention?

- Check whether Urinary retention is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Co-codamol:

Co-codamol (2,364 reports)

Urinary retention treatments and more:

Urinary retention (42,971 reports)

How severe was Urinary retention and when was it recovered:

Urinary retention in Co-codamol

Expand to all the drugs that have ingredients of acetaminophen; codeine phosphate:

Urinary retention and drugs with ingredients of acetaminophen; codeine phosphate (242 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Co-codamol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Urinary retention:

Urinary retention (1,572 drugs)

Browse all the conditions that are associated with Urinary retention:

Urinary retention (1,735 conditions)

Related publications that referenced our studies

Schattner A, Al-Bewerat A, "Levetiracetam (Keppra), urinary retention and literature search", A fatty cause of renal failure; what is your diagnosis?, 2016 Oct .
Schattner A, Al-Bewerat A, "Levetiracetam (Keppra), urinary retention and literature search", A fatty cause of renal failure; what is your diagnosis?, 2016 Oct .

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; codeine phosphate (the active ingredients of Co-codamol) and Co-codamol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.