Cobamamide and Adverse event - a phase IV clinical study of FDA data

Summary:

Adverse event is reported as a side effect among people who take Cobamamide (dibencozide), especially for people who are female, 50-59 old, also take Spironolactone, and have Asthma.

The phase IV clinical study analyzes which people have Adverse event when taking Cobamamide. It is created by eHealthMe based on reports of 1,046 people who have side effects when taking Cobamamide from the FDA, and is updated regularly.

What is Cobamamide?

Cobamamide has active ingredients of dibencozide. eHealthMe is studying from 1,046 Cobamamide users. Check the latest studies of Cobamamide.

What is Adverse event?

Adverse event is found to be associated with 1,684 drugs and 1,666 conditions by eHealthMe. Check the latest studies of Adverse event.



On Jul, 19, 2026

1,046 people reported to have side effects when taking Cobamamide.
Among them, 44 people (4.21%) have Adverse event.

Could Cobamamide cause Adverse event?

Among these 44 people:

What is the gender of people who have Adverse event when taking Cobamamide? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Adverse event when taking Cobamamide? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 97.5 %
  • 60+: 2.5 %

What are other drugs people take besides Cobamamide? *

  1. Sodium Chloride: 42 people, 95.45%
  2. Apixaban: 42 people, 95.45%
  3. Liothyronine Sodium: 42 people, 95.45%
  4. Prednisone: 42 people, 95.45%
  5. Budesonide: 42 people, 95.45%
  6. Sodium Bicarbonate: 42 people, 95.45%
  7. Ergocalciferol: 42 people, 95.45%
  8. Spironolactone: 42 people, 95.45%
  9. Clonazepam: 41 people, 93.18%
  10. Bupropion Hydrochloride: 41 people, 93.18%

What are other side effects people have besides Adverse event? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 42 people, 95.45%
  2. Fibromyalgia (a long-term condition which causes pain all over the body): 42 people, 95.45%
  3. Ejection Fraction Abnormal (abnormality in percentage of blood that is pumped out of a filled ventricle as a result of a heartbeat): 42 people, 95.45%
  4. Headache (pain in head): 42 people, 95.45%
  5. High Blood Pressure: 42 people, 95.45%
  6. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 42 people, 95.45%
  7. Carpal Tunnel Syndrome (nerve compression at wrist results numbness weakness, pain , swelling): 42 people, 95.45%
  8. Cardiac Disorder: 42 people, 95.45%
  9. Burning Sensation: 42 people, 95.45%
  10. Obstructive Sleep Apnea Syndrome (a sleep disorder that involves cessation or significant decrease in airflow in the presence of breathing effort): 42 people, 95.45%

What are the existing conditions these people have? *

  1. Asthma: 25 people, 56.82%
  2. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 1 person, 2.27%
  3. Idiopathic Thrombocytopenic Purpura (Itp) (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 1 person, 2.27%

* Approximation only. Some reports may have incomplete information.

Do you take Cobamamide and have Adverse event?

- Check whether Adverse event is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cobamamide:

Adverse event treatments and more:

How severe was Adverse event and when was it recovered:

Expand to all the drugs that have ingredients of dibencozide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cobamamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Adverse event:

Browse all the conditions that are associated with Adverse event:


How the study uses the data?

The study uses data from the FDA. It is based on dibencozide (the active ingredients of Cobamamide) and Cobamamide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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