Cobamamide and Death - a phase IV clinical study of FDA data

Summary:

Death is reported as a side effect among people who take Cobamamide (dibencozide), especially for people who are male, 60+ old, also take Eliquis, and have Skin cancer.

The study is created by eHealthMe based on reports of 1,046 people who have side effects when taking Cobamamide from the FDA, and is updated regularly.

What is Cobamamide?

Cobamamide has active ingredients of dibencozide. eHealthMe is studying from 1,046 Cobamamide users. Check the latest studies of Cobamamide.

On Jul, 16, 2026

1,046 people reported to have side effects when taking Cobamamide.
Among them, 35 people (3.35%) died.

Among these 35 people:

What is the gender of people who died when taking Cobamamide? *

female: 45.45 %
male: 54.55 %

What is the age of people who died when taking Cobamamide? *

What are other drugs people take besides Cobamamide? *

What are other side effects people have before they died? *

Dyspnea (difficult or laboured breathing): 6 people, 17.14%
Joint Pain: 5 people, 14.29%
Nausea (feeling of having an urge to vomit): 5 people, 14.29%
Nausea And Vomiting: 5 people, 14.29%
Weight Increased: 4 people, 11.43%
Interstitial Lung Disease: 4 people, 11.43%
Hypoaesthesia (reduced sense of touch or sensation): 4 people, 11.43%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 4 people, 11.43%
Weight Decreased: 4 people, 11.43%
Fever: 4 people, 11.43%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 3 people, 8.57%
Skin Cancer: 3 people, 8.57%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 5.71%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 2.86%
Immune System Disorder: 1 person, 2.86%
Cervical Cord Compression (compression of spinal cord at site of cervical vertebrae): 1 person, 2.86%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 2.86%
Diabetes: 1 person, 2.86%
Diarrhea: 1 person, 2.86%
Disease Complication: 1 person, 2.86%

* Approximation only. Some reports may have incomplete information.

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cobamamide:

Cobamamide (1,046 reports)

Expand to all the drugs that have ingredients of dibencozide:

Death and drugs with ingredients of dibencozide (76 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cobamamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Death:

Death (3,125 drugs)

Browse all the conditions that are associated with Death:

Death (3,686 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on dibencozide (the active ingredients of Cobamamide) and Cobamamide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.