Codeine and Bacteraemia - a phase IV clinical study of FDA data

Summary:

Bacteraemia is reported as a side effect among people who take Codeine (codeine sulfate), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Aspirin, and have Short-bowel syndrome.

The phase IV clinical study analyzes which people have Bacteraemia when taking Codeine. It is created by eHealthMe based on reports of 41,713 people who have side effects when taking Codeine from the FDA, and is updated regularly.

What is Codeine?

Codeine has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 42,342 Codeine users. Check the latest studies of Codeine.

What is Bacteraemia?

Bacteraemia (presence of bacteria in the blood) is found to be associated with 1,037 drugs and 1,511 conditions by eHealthMe. Check the latest studies of Bacteraemia.



On Jan, 27, 2026

41,713 people reported to have side effects when taking Codeine.
Among them, 29 people (0.07%) have Bacteraemia.

Could Codeine cause Bacteraemia?

Among these 29 people:

How long have people been on Codeine when they have Bacteraemia? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Bacteraemia when taking Codeine? *

  • female: 37.04 %
  • male: 62.96 %

What is the age of people who have Bacteraemia when taking Codeine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 3.7 %
  • 40-49: 7.41 %
  • 50-59: 48.15 %
  • 60+: 40.74 %

What are other drugs people take besides Codeine? *

  1. Aspirin: 9 people, 31.03%
  2. Vitamin D3: 8 people, 27.59%
  3. Xarelto: 6 people, 20.69%
  4. Dexamethasone: 6 people, 20.69%
  5. Tpn: 5 people, 17.24%
  6. Acetaminophen: 5 people, 17.24%
  7. Lasix: 5 people, 17.24%
  8. Vitamin B12: 5 people, 17.24%
  9. Heparin: 5 people, 17.24%
  10. Vancomycin: 5 people, 17.24%

What are other side effects people have besides Bacteraemia? *

  1. Pneumonia: 9 people, 31.03%
  2. Nausea (feeling of having an urge to vomit): 5 people, 17.24%
  3. Urinary Tract Infection: 5 people, 17.24%
  4. Escherichia Bacteraemia (presence of bacteria escherichia coli in the blood): 4 people, 13.79%
  5. Fever: 4 people, 13.79%
  6. Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking): 4 people, 13.79%
  7. Gamma-Glutamyltransferase Increased: 4 people, 13.79%
  8. Hepatic Function Abnormal: 4 people, 13.79%
  9. Stomatitis (inflammation of mucous membrane of mouth): 4 people, 13.79%
  10. Infection: 4 people, 13.79%

What are the existing conditions these people have? *

  1. Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 9 people, 31.03%
  2. Pneumonia: 8 people, 27.59%
  3. High Blood Pressure: 6 people, 20.69%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 20.69%
  5. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 17.24%
  6. The Flu (the flu is caused by an influenza virus): 4 people, 13.79%
  7. Diarrhea: 4 people, 13.79%
  8. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 13.79%
  9. Anaemia (lack of blood): 3 people, 10.34%
  10. Cardiac Failure Congestive: 3 people, 10.34%

* Approximation only. Some reports may have incomplete information.

Do you take Codeine and have Bacteraemia?

- Check whether Bacteraemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Codeine:

Bacteraemia treatments and more:

How severe was Bacteraemia and when was it recovered:

Expand to all the drugs that have ingredients of codeine sulfate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Codeine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bacteraemia:

Browse all the conditions that are associated with Bacteraemia:


How the study uses the data?

The study uses data from the FDA. It is based on codeine sulfate (the active ingredients of Codeine) and Codeine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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