Codeine and Embolism - a phase IV clinical study of FDA data

Summary:

Embolism is reported as a side effect among people who take Codeine (codeine sulfate), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Paracetamol, and have Nausea.

The phase IV clinical study analyzes which people have Embolism when taking Codeine. It is created by eHealthMe based on reports of 41,713 people who have side effects when taking Codeine from the FDA, and is updated regularly.

What is Codeine?

Codeine has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 42,342 Codeine users. Check the latest studies of Codeine.

What is Embolism?

Embolism (obstruction of an artery, typically by a clot of blood or an air bubble) is found to be associated with 721 drugs and 919 conditions by eHealthMe. Check the latest studies of Embolism.

On Jun, 18, 2026

41,713 people reported to have side effects when taking Codeine.
Among them, 14 people (0.03%) have Embolism.

Among these 14 people:

How long have people been on Codeine when they have Embolism? *

What is the gender of people who have Embolism when taking Codeine? *

female: 40 %
male: 60 %

What is the age of people who have Embolism when taking Codeine? *

What are other drugs people take besides Codeine? *

Paracetamol: 7 people, 50.00%
Senna: 5 people, 35.71%
Ondansetron: 5 people, 35.71%
Aspirin: 3 people, 21.43%
Clopidogrel: 2 people, 14.29%
Piperacillin And Tazobactam: 2 people, 14.29%
Zopiclone: 2 people, 14.29%
Movicol: 2 people, 14.29%
Xarelto: 2 people, 14.29%
Carboplatin: 1 person, 7.14%

What are other side effects people have besides Embolism? *

Anaemia (lack of blood): 3 people, 21.43%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 2 people, 14.29%
Pulmonary Embolism (blockage of the main artery of the lung): 2 people, 14.29%
Arrhythmias (irregular heartbeat): 2 people, 14.29%
Infection: 2 people, 14.29%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 2 people, 14.29%
Device Related Infection: 1 person, 7.14%
Diarrhea: 1 person, 7.14%
Disease Progression: 1 person, 7.14%
Extremity Necrosis (death of body tissue of arms and legs): 1 person, 7.14%

What are the existing conditions these people have? *

Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 6 people, 42.86%
Constipation: 6 people, 42.86%
Nausea (feeling of having an urge to vomit): 6 people, 42.86%
Infection: 3 people, 21.43%
Blood Calcium Decreased: 3 people, 21.43%
Blood Potassium Decreased: 3 people, 21.43%
Tumor Lysis Syndrome: 3 people, 21.43%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 14.29%
Blood Folate Decreased: 2 people, 14.29%
Breast Cancer: 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Codeine and have Embolism?

- Check whether Embolism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Codeine:

Codeine (42,342 reports)

Embolism treatments and more:

Embolism (13,418 reports)

Browse all side effects of Codeine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Embolism:

Embolism (721 drugs)

Browse all the conditions that are associated with Embolism:

Embolism (919 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on codeine sulfate (the active ingredients of Codeine) and Codeine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.