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Codeine and Gingivitis aggravated - a phase IV clinical study of FDA data

Summary:

Gingivitis aggravated is reported as a side effect among people who take Codeine (codeine sulfate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Esbriet, and have Idiopathic pulmonary fibrosis.

The phase IV clinical study analyzes which people have Gingivitis aggravated when taking Codeine. It is created by eHealthMe based on reports of 41,713 people who have side effects when taking Codeine from the FDA, and is updated regularly.

What is Codeine?

Codeine has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 42,341 Codeine users. Check the latest studies of Codeine.

What is Gingivitis aggravated?

Gingivitis aggravated (infection of gums) is found to be associated with 759 drugs and 206 conditions by eHealthMe. Check the latest studies of Gingivitis aggravated.

On Oct, 20, 2025

41,713 people reported to have side effects when taking Codeine.
Among them, 59 people (0.14%) have Gingivitis aggravated.

Could Codeine cause Gingivitis aggravated?

Among these 59 people:

How long have people been on Codeine when they have Gingivitis aggravated? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Gingivitis aggravated when taking Codeine? *

  • female: 61.7 %
  • male: 38.3 %

What is the age of people who have Gingivitis aggravated when taking Codeine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 27.27 %
  • 30-39: 9.09 %
  • 40-49: 9.09 %
  • 50-59: 15.91 %
  • 60+: 38.64 %

What are other drugs people take besides Codeine? *

  1. Esbriet: 13 people, 22.03%
  2. Advair Hfa: 12 people, 20.34%
  3. Spiriva: 12 people, 20.34%
  4. Vitamin C: 9 people, 15.25%
  5. Concerta: 8 people, 13.56%
  6. Vyvanse: 8 people, 13.56%
  7. Ventolin: 8 people, 13.56%
  8. Ilaris: 7 people, 11.86%
  9. Zoloft: 7 people, 11.86%
  10. Amlodipine: 6 people, 10.17%

What are other side effects people have besides Gingivitis aggravated? *

  1. Diarrhea: 33 people, 55.93%
  2. Nausea (feeling of having an urge to vomit): 27 people, 45.76%
  3. Sinusitis (inflammation of sinus): 26 people, 44.07%
  4. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 25 people, 42.37%
  5. Cough: 24 people, 40.68%
  6. Fatigue (feeling of tiredness): 23 people, 38.98%
  7. Sinus Congestion (blockage of sinus): 20 people, 33.90%
  8. Headache (pain in head): 20 people, 33.90%
  9. Fever: 17 people, 28.81%
  10. Lower Respiratory Tract Infection: 17 people, 28.81%

What are the existing conditions these people have? *

  1. Asthma: 15 people, 25.42%
  2. Idiopathic Pulmonary Fibrosis (chronic lung disease): 15 people, 25.42%
  3. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 11 people, 18.64%
  4. Disturbance In Attention: 8 people, 13.56%
  5. Familial Mediterranean Fever (genetic disease recurring attacks of abdominal pain, fever, pleurisy, arthritis, and rash): 7 people, 11.86%
  6. Constipation: 7 people, 11.86%
  7. Breast Cancer Metastatic: 5 people, 8.47%
  8. Insomnia (sleeplessness): 5 people, 8.47%
  9. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 5 people, 8.47%
  10. Aortic Valve Incompetence: 4 people, 6.78%

* Approximation only. Some reports may have incomplete information.

Do you take Codeine and have Gingivitis aggravated?

- Check whether Gingivitis aggravated is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Codeine:

Gingivitis aggravated treatments and more:

How severe was Gingivitis aggravated and when was it recovered:

Expand to all the drugs that have ingredients of codeine sulfate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Codeine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Gingivitis aggravated:

Browse all the conditions that are associated with Gingivitis aggravated:

Drugs similar to Codeine and Gingivitis aggravated :

How the study uses the data?

The study uses data from the FDA. It is based on codeine sulfate (the active ingredients of Codeine) and Codeine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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