Codeine and Hyperlipidemia - a phase IV clinical study of FDA data

Summary:

Hyperlipidemia is reported as a side effect among people who take Codeine (codeine sulfate), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Humira, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Hyperlipidemia when taking Codeine. It is created by eHealthMe based on reports of 41,713 people who have side effects when taking Codeine from the FDA, and is updated regularly.

What is Codeine?

Codeine has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 42,341 Codeine users. Check the latest studies of Codeine.

What is Hyperlipidemia?

Hyperlipidemia (presence of excess lipids in the blood) is found to be associated with 2,518 drugs and 3,539 conditions by eHealthMe. Check the latest studies of Hyperlipidemia.



On Oct, 13, 2025

41,713 people reported to have side effects when taking Codeine.
Among them, 1,352 people (3.24%) have Hyperlipidemia.

Could Codeine cause Hyperlipidemia?

Among these 1,352 people:

How long have people been on Codeine when they have Hyperlipidemia? *

  • < 1 month: 66.67 %
  • 1 - 6 months: 33.33 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hyperlipidemia when taking Codeine? *

  • female: 97.82 %
  • male: 2.18 %

What is the age of people who have Hyperlipidemia when taking Codeine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.22 %
  • 20-29: 0.22 %
  • 30-39: 0.43 %
  • 40-49: 53.96 %
  • 50-59: 29.86 %
  • 60+: 15.31 %

What are other drugs people take besides Codeine? *

  1. Humira: 1,176 people, 86.98%
  2. Orencia: 1,146 people, 84.76%
  3. Actemra: 1,144 people, 84.62%
  4. Enbrel: 1,140 people, 84.32%
  5. Xeljanz: 1,084 people, 80.18%
  6. Arava: 1,062 people, 78.55%
  7. Remicade: 1,051 people, 77.74%
  8. Cimzia: 1,012 people, 74.85%
  9. Simponi: 997 people, 73.74%
  10. Acetaminophen: 930 people, 68.79%

What are other side effects people have besides Hyperlipidemia? *

  1. Joint Pain: 1,022 people, 75.59%
  2. Drug Ineffective: 982 people, 72.63%
  3. Fibromyalgia (a long-term condition which causes pain all over the body): 946 people, 69.97%
  4. Joint Swelling: 902 people, 66.72%
  5. Fatigue (feeling of tiredness): 897 people, 66.35%
  6. Swelling: 893 people, 66.05%
  7. Synovitis (inflammation of the synovial membrane): 869 people, 64.28%
  8. Hair Loss: 865 people, 63.98%
  9. Drug Intolerance (drug sensitivity): 859 people, 63.54%
  10. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 856 people, 63.31%

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1,239 people, 91.64%
  2. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 463 people, 34.25%
  3. Psoriasis (immune-mediated disease that affects the skin): 348 people, 25.74%
  4. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 245 people, 18.12%
  5. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 205 people, 15.16%
  6. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 200 people, 14.79%
  7. Ankylosing Spondylitis (type of arthritis affecting the spine): 119 people, 8.80%
  8. Stress And Anxiety: 119 people, 8.80%
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints): 118 people, 8.73%
  10. Indigestion: 109 people, 8.06%

* Approximation only. Some reports may have incomplete information.

Do you take Codeine and have Hyperlipidemia?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Codeine:

Hyperlipidemia treatments and more:

How severe was Hyperlipidemia and when was it recovered:

Expand to all the drugs that have ingredients of codeine sulfate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Codeine side effects:

Browse all side effects of Codeine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Hyperlipidemia:

Browse all the drugs that are associated with Hyperlipidemia:

Common conditions associated with Hyperlipidemia:

Browse all the conditions that are associated with Hyperlipidemia:

Drugs similar to Codeine and Hyperlipidemia :


How the study uses the data?

The study uses data from the FDA. It is based on codeine sulfate (the active ingredients of Codeine) and Codeine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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