Codeine and Psoriasis aggravated - a phase IV clinical study of FDA data

Summary:

Psoriasis aggravated is reported as a side effect among people who take Codeine (codeine sulfate), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Enbrel, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Psoriasis aggravated when taking Codeine. It is created by eHealthMe based on reports of 41,713 people who have side effects when taking Codeine from the FDA, and is updated regularly.

What is Codeine?

Codeine has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 42,341 Codeine users. Check the latest studies of Codeine.

What is Psoriasis aggravated?

Psoriasis aggravated (immune-mediated disease that affects the skin) is found to be associated with 1,287 drugs and 454 conditions by eHealthMe. Check the latest studies of Psoriasis aggravated.



On Nov, 19, 2025

41,713 people reported to have side effects when taking Codeine.
Among them, 852 people (2.04%) have Psoriasis aggravated.

Could Codeine cause Psoriasis aggravated?

Among these 852 people:

How long have people been on Codeine when they have Psoriasis aggravated? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Psoriasis aggravated when taking Codeine? *

  • female: 95.8 %
  • male: 4.2 %

What is the age of people who have Psoriasis aggravated when taking Codeine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.88 %
  • 30-39: 16.64 %
  • 40-49: 13.31 %
  • 50-59: 43.08 %
  • 60+: 26.09 %

What are other drugs people take besides Codeine? *

  1. Enbrel: 714 people, 83.80%
  2. Humira: 710 people, 83.33%
  3. Remicade: 663 people, 77.82%
  4. Demerol: 628 people, 73.71%
  5. Xeljanz: 495 people, 58.10%
  6. Orencia: 450 people, 52.82%
  7. Lyrica: 377 people, 44.25%
  8. Rituxan: 361 people, 42.37%
  9. Morphine: 358 people, 42.02%
  10. Actemra: 314 people, 36.85%

What are other side effects people have besides Psoriasis aggravated? *

  1. Drug Ineffective: 722 people, 84.74%
  2. Drug Hypersensitivity: 712 people, 83.57%
  3. Drug Intolerance (drug sensitivity): 696 people, 81.69%
  4. Rashes (redness): 671 people, 78.76%
  5. Upper Respiratory Tract Infection: 667 people, 78.29%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 622 people, 73.00%
  7. Joint Swelling: 592 people, 69.48%
  8. Infusion Related Reaction: 566 people, 66.43%
  9. High Blood Pressure: 528 people, 61.97%
  10. Fever: 489 people, 57.39%

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 691 people, 81.10%
  2. Herpes Zoster: 311 people, 36.50%
  3. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 262 people, 30.75%
  4. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 59 people, 6.92%
  5. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 52 people, 6.10%
  6. Ankylosing Spondylitis (type of arthritis affecting the spine): 40 people, 4.69%
  7. Joint Pain: 20 people, 2.35%
  8. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 17 people, 2.00%
  9. Depression: 12 people, 1.41%
  10. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 11 people, 1.29%

* Approximation only. Some reports may have incomplete information.

Do you take Codeine and have Psoriasis aggravated?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Codeine:

Psoriasis aggravated treatments and more:

How severe was Psoriasis aggravated and when was it recovered:

Expand to all the drugs that have ingredients of codeine sulfate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Codeine side effects:

Browse all side effects of Codeine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Psoriasis aggravated:

Browse all the drugs that are associated with Psoriasis aggravated:

Common conditions associated with Psoriasis aggravated:

Browse all the conditions that are associated with Psoriasis aggravated:

Drugs similar to Codeine and Psoriasis aggravated :


How the study uses the data?

The study uses data from the FDA. It is based on codeine sulfate (the active ingredients of Codeine) and Codeine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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