Codeine and Strabismus - a phase IV clinical study of FDA data


Strabismus is reported only by a few people who take Codeine.

The phase IV clinical study analyzes which people take Codeine and have Strabismus. It is created by eHealthMe based on reports of 33,014 people who have side effects while taking Codeine from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On May, 26, 2023

33,014 people reported to have side effects when taking Codeine.
Among them, 4 people (0.01%) have Strabismus.

What is Codeine?

Codeine has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 33,621 Codeine users for its effectiveness, alternative drugs and more.

What is Strabismus?

Strabismus (a disorder in which the two eyes do not line up in the same direction) is found to be associated with 1,200 drugs and 737 conditions by eHealthMe.

Number of Codeine and Strabismus reports submitted per year:

Could Codeine cause Strabismus?

Gender of people who have Strabismus when taking Codeine *:

  • female: 75 %
  • male: 25 %

Age of people who have Strabismus when taking Codeine *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 66.67 %
  • 40-49: 0.0 %
  • 50-59: 33.33 %
  • 60+: 0.0 %

Common drugs people take besides Codeine *:

  1. Paracetamol: 2 people, 50.00%
  2. Zolpidem: 1 person, 25.00%
  3. Xyrem: 1 person, 25.00%
  4. Potassium: 1 person, 25.00%
  5. Pancreatin: 1 person, 25.00%
  6. Neurontin: 1 person, 25.00%
  7. Lyrica: 1 person, 25.00%
  8. Lamictal: 1 person, 25.00%
  9. Clotrimazole: 1 person, 25.00%
  10. Cefadroxil: 1 person, 25.00%

Common side effects people have besides Strabismus *:

  1. Withdrawal Syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance): 1 person, 25.00%
  2. Dizziness: 1 person, 25.00%
  3. Hallucinations (sensations that appear real but are created by your mind): 1 person, 25.00%
  4. Gait Disturbance: 1 person, 25.00%
  5. Feeling Of Body Temperature Change: 1 person, 25.00%
  6. Fall: 1 person, 25.00%
  7. Fainting (loss of consciousness and postural tone): 1 person, 25.00%
  8. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 25.00%
  9. Emotional Poverty: 1 person, 25.00%
  10. Drug Dependence: 1 person, 25.00%

Common conditions people have *:

  1. Sleep Disorder: 1 person, 25.00%
  2. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1 person, 25.00%
  3. Neuralgia (pain in one or more nerves): 1 person, 25.00%
  4. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 25.00%
  5. Headache (pain in head): 1 person, 25.00%
  6. Drowsiness: 1 person, 25.00%
  7. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 25.00%

* Approximation only. Some reports may have incomplete information.

Do you take Codeine and have Strabismus?

Check whether Strabismus is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Strabismus and when was it recovered:

Expand to all the drugs that have ingredients of codeine sulfate:

Alternative drugs to, pros and cons of Codeine:

Common Codeine side effects:

Browse all side effects of Codeine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Strabismus treatments and more:

COVID vaccines that are related to Strabismus:

Common drugs associated with Strabismus:

All the drugs that are associated with Strabismus:

Common conditions associated with Strabismus:

All the conditions that are associated with Strabismus:

How the study uses the data?

The study uses data from the FDA. It is based on codeine sulfate (the active ingredients of Codeine) and Codeine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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