Codeine and Thyroid mass - a phase IV clinical study of FDA data

Summary:

Thyroid mass is reported as a side effect among people who take Codeine (codeine sulfate), especially for people who are female, 60+ old, also take Plaquenil, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Thyroid mass when taking Codeine. It is created by eHealthMe based on reports of 41,713 people who have side effects when taking Codeine from the FDA, and is updated regularly.

What is Codeine?

Codeine has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 42,341 Codeine users. Check the latest studies of Codeine.

What is Thyroid mass?

Thyroid mass is found to be associated with 536 drugs and 386 conditions by eHealthMe. Check the latest studies of Thyroid mass.

On Sep, 22, 2025

41,713 people reported to have side effects when taking Codeine.
Among them, 15 people (0.04%) have Thyroid mass.

Among these 15 people:

What is the gender of people who have Thyroid mass when taking Codeine? *

female: 55.56 %
male: 44.44 %

What is the age of people who have Thyroid mass when taking Codeine? *

What are other drugs people take besides Codeine? *

What are other side effects people have besides Thyroid mass? *

Pain In Extremity: 13 people, 86.67%
Dizziness: 12 people, 80.00%
Nausea (feeling of having an urge to vomit): 11 people, 73.33%
High Blood Pressure: 11 people, 73.33%
Hypoaesthesia (reduced sense of touch or sensation): 10 people, 66.67%
Joint Pain: 10 people, 66.67%
Neck Pain: 10 people, 66.67%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 10 people, 66.67%
Malaise (a feeling of general discomfort or uneasiness): 10 people, 66.67%
Oropharyngeal Pain: 10 people, 66.67%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 10 people, 66.67%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 13.33%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 6.67%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 6.67%
High Blood Pressure: 1 person, 6.67%
Glaucoma (increased fluid pressure in the eye with vision loss): 1 person, 6.67%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Codeine and have Thyroid mass?

- Check whether Thyroid mass is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Codeine:

Codeine (42,341 reports)

Thyroid mass treatments and more:

Thyroid mass (4,811 reports)

How severe was Thyroid mass and when was it recovered:

Thyroid mass in Codeine

Browse all side effects of Codeine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Thyroid mass:

Thyroid mass (536 drugs)

Browse all the conditions that are associated with Thyroid mass:

Thyroid mass (386 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on codeine sulfate (the active ingredients of Codeine) and Codeine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.